Esther Verkade
Overview
Explore the profile of Esther Verkade including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
422
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Recent Articles
1.
Verkade E, Shen W, Hovingh M, Mulder N, de Bruyn K, Koehorst M, et al.
Clin Sci (Lond)
. 2023 Nov;
137(21):1637-1650.
PMID: 37910096
Cyp2c70-deficient mice have a human-like bile acid (BA) composition due to their inability to convert chenodeoxycholic acid (CDCA) into rodent-specific muricholic acids (MCAs). However, the hydrophobic BA composition in these...
2.
Palmiotti A, de Vries H, Hovingh M, Koehorst M, Mulder N, Verkade E, et al.
Biomedicines
. 2023 Sep;
11(9).
PMID: 37760936
Bile acids (BAs) and their signaling pathways have been identified as therapeutic targets for liver and metabolic diseases. We generated (KO) mice that were not able to convert chenodeoxycholic acid...
3.
Evangelakos I, Heeren J, Verkade E, Kuipers F
Semin Immunopathol
. 2021 Jul;
43(4):577-590.
PMID: 34236487
Bile acids and their signaling pathways are increasingly recognized as potential therapeutic targets for cholestatic and metabolic liver diseases. This review summarizes new insights in bile acid physiology, focusing on...
4.
de Boer J, Verkade E, Mulder N, de Vries H, Huijkman N, Koehorst M, et al.
J Lipid Res
. 2019 Sep;
61(3):291-305.
PMID: 31506275
Bile acids (BAs) facilitate intestinal absorption of lipid-soluble nutrients and modulate various metabolic pathways through the farnesoid X receptor (FXR) and Takeda G-protein-coupled receptor 5. These receptors are targets for...
5.
Palmer A, Xu M, Zhu Y, Pirtskhalava T, Weivoda M, Hachfeld C, et al.
Aging Cell
. 2019 Mar;
18(3):e12950.
PMID: 30907060
Adipose tissue inflammation and dysfunction are associated with obesity-related insulin resistance and diabetes, but mechanisms underlying this relationship are unclear. Although senescent cells accumulate in adipose tissue of obese humans...
6.
de Boer J, Bloks V, Verkade E, Heiner-Fokkema M, Kuipers F
Curr Opin Lipidol
. 2018 Mar;
29(3):194-202.
PMID: 29553998
Purpose Of Review: There is a growing awareness that individual bile acid species exert different physiological functions, beyond their classical roles in bile formation and fat absorption, due to differential...