Esther Fuente-Martin
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Explore the profile of Esther Fuente-Martin including associated specialties, affiliations and a list of published articles.
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Articles
22
Citations
668
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Recent Articles
1.
Lorenzo P, Vazquez E, Lopez-Noriega L, Fuente-Martin E, Mellado-Gil J, Franco J, et al.
Theranostics
. 2021 Jun;
11(14):6983-7004.
PMID: 34093866
We recently demonstrated that the 'Metabesity' factor HMG20A regulates islet beta-cell functional maturity and adaptation to physiological stress such as pregnancy and pre-diabetes. HMG20A also dictates central nervous system (CNS)...
2.
Fuente-Martin E, Mellado-Gil J, Cobo-Vuilleumier N, Martin-Montalvo A, Romero-Zerbo S, Diaz Contreras I, et al.
Genes (Basel)
. 2019 May;
10(5).
PMID: 31072002
The high prevalence of type 2 diabetes mellitus (T2DM), together with the fact that current treatments are only palliative and do not avoid major secondary complications, reveals the need for...
3.
Cobo-Vuilleumier N, Lorenzo P, Rodriguez N, Herrera Gomez I, Fuente-Martin E, Lopez-Noriega L, et al.
Nat Commun
. 2018 Apr;
9(1):1488.
PMID: 29662071
Type 1 diabetes mellitus (T1DM) is due to the selective destruction of islet beta cells by immune cells. Current therapies focused on repressing the immune attack or stimulating beta cell...
4.
Mellado-Gil J, Fuente-Martin E, Lorenzo P, Cobo-Vuilleumier N, Lopez-Noriega L, Martin-Montalvo A, et al.
Cell Death Dis
. 2018 Feb;
9(3):279.
PMID: 29449530
HMG20A (also known as iBRAF) is a chromatin factor involved in neuronal differentiation and maturation. Recently small nucleotide polymorphisms (SNPs) in the HMG20A gene have been linked to type 2...
5.
Argente-Arizon P, Ros P, Diaz F, Fuente-Martin E, Castro-Gonzalez D, Sanchez-Garrido M, et al.
Biol Sex Differ
. 2016 May;
7:26.
PMID: 27195103
Background: Males and females respond differently to diverse metabolic situations. Being raised in a small litter is reported to cause overnutrition that increases weight gain and predisposes an individual to...
6.
Fuente-Martin E, Garcia-Caceres C, Argente-Arizon P, Diaz F, Granado M, Freire-Regatillo A, et al.
Sci Rep
. 2016 Mar;
6:23673.
PMID: 27026049
Hypothalamic astrocytes can respond to metabolic signals, such as leptin and insulin, to modulate adjacent neuronal circuits and systemic metabolism. Ghrelin regulates appetite, adiposity and glucose metabolism, but little is...
7.
Kabra D, Pfuhlmann K, Garcia-Caceres C, Schriever S, Casquero Garcia V, Kebede A, et al.
Nat Commun
. 2016 Mar;
7:10782.
PMID: 26923837
Hypothalamic leptin signalling has a key role in food intake and energy-balance control and is often impaired in obese individuals. Here we identify histone deacetylase 5 (HDAC5) as a regulator...
8.
Mellado-Gil J, Jimenez-Moreno C, Martin-Montalvo A, Isabel Alvarez-Mercado A, Fuente-Martin E, Cobo-Vuilleumier N, et al.
Diabetologia
. 2016 Jan;
59(4):755-65.
PMID: 26813254
Aims/hypothesis: A strategy to enhance pancreatic islet functional beta cell mass (BCM) while restraining inflammation, through the manipulation of molecular and cellular targets, would provide a means to counteract the...
9.
Lorenzo P, Fuente-Martin E, Brun T, Cobo-Vuilleumier N, Jimenez-Moreno C, G Herrera Gomez I, et al.
Sci Rep
. 2015 Oct;
5:15672.
PMID: 26503027
PAX4 is a key regulator of pancreatic islet development whilst in adult acute overexpression protects β-cells against stress-induced apoptosis and stimulates proliferation. Nonetheless, sustained PAX4 expression promotes β-cell dedifferentiation and...
10.
Jimenez-Moreno C, Herrera-Gomez I, Lopez-Noriega L, Lorenzo P, Cobo-Vuilleumier N, Fuente-Martin E, et al.
Curr Gene Ther
. 2015 Jul;
15(4):436-46.
PMID: 26122098
Successful normalization of blood glucose in patients transplanted with pancreatic islets isolated from cadaveric donors established the proof-of-concept that Type 1 Diabetes Mellitus is a curable disease. Nonetheless, major caveats...