Erwin Defensor
Overview
Explore the profile of Erwin Defensor including associated specialties, affiliations and a list of published articles.
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6
Citations
389
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Recent Articles
1.
Shamloo S, Defensor E, Ciari P, Ogawa G, Vidano L, Lin J, et al.
Front Neurosci
. 2023 Apr;
17:1150156.
PMID: 37090796
There is an urgent need for therapeutic approaches that can prevent or limit neuroinflammatory processes and prevent neuronal degeneration. Photobiomodulation (PBM), the therapeutic use of specific wavelengths of light, is...
2.
Evans A, Defensor E, Shamloo M
Front Pharmacol
. 2022 Dec;
13:1030609.
PMID: 36532725
Locus coeruleus (LC) noradrenergic (NE) neurons supply the main adrenergic input to the forebrain. NE is a dual modulator of cognition and neuroinflammation. NE neurons of the LC are particularly...
3.
Nwagwu C, Defensor E, Jiang M, Rolle-McFarland D, Carbonell A, Carbonell W
Lab Anim (NY)
. 2020 Jul;
49(8):227-232.
PMID: 32690932
Despite several therapeutics showing promise in nonclinical studies, survival from ovarian cancer remains poor. New technologies are urgently needed to optimize the translation of nonclinical studies into clinical successes. While...
4.
Bieri G, Brahic M, Bousset L, Couthouis J, Kramer N, Ma R, et al.
Acta Neuropathol
. 2019 Mar;
137(6):961-980.
PMID: 30927072
Progressive aggregation of the protein alpha-synuclein (α-syn) and loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc) are key histopathological hallmarks of Parkinson's disease (PD). Accruing evidence suggests...
5.
Briggs D, Defensor E, Ardestani P, Yi B, Halpain M, Seabrook G, et al.
eNeuro
. 2017 Jul;
4(4).
PMID: 28721361
Emerging evidence suggests that endoplasmic reticulum (ER) stress may be involved in the pathogenesis of Alzheimer's disease (AD). Recently, pharmacological modulation of the eukaryotic translation initiation factor-2 (eIF2α) pathway was...
6.
Min S, Chen X, Tracy T, Li Y, Zhou Y, Wang C, et al.
Nat Med
. 2015 Sep;
21(10):1154-62.
PMID: 26390242
Tauopathies, including frontotemporal dementia (FTD) and Alzheimer's disease (AD), are neurodegenerative diseases in which tau fibrils accumulate. Recent evidence supports soluble tau species as the major toxic species. How soluble...