Erin D Lucas
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Explore the profile of Erin D Lucas including associated specialties, affiliations and a list of published articles.
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14
Citations
206
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Recent Articles
1.
Kantheti U, Forward T, Lucas E, Schafer J, Tamburini P, Burchill M, et al.
Sci Adv
. 2025 Jan;
11(5):eadt3044.
PMID: 39879305
Programmed cell death protein 1 (PD-1) and programmed death ligand 1 (PD-L1) interactions are targets for immunotherapies aimed to reinvigorate T cell function. Recently, it was documented that PD-L1 regulates...
2.
Mills T, Kain B, Burchill M, Danis E, Lucas E, Culp-Hill R, et al.
Cell Stem Cell
. 2024 Oct;
31(11):1630-1649.e8.
PMID: 39413777
Here, we investigate the contribution of long-term hematopoietic stem cells (HSCs) to trained immunity (TI) in the setting of chronic autoimmune disease. Using a mouse model of systemic lupus erythematosus...
3.
Lucas E, Huggins M, Peng C, OConnor C, Gress A, Thefaine C, et al.
Sci Immunol
. 2024 Jun;
9(96):eadj8356.
PMID: 38941479
KLRG1 CD8 T cells persist for months after clearance of acute infections and maintain high levels of effector molecules, contributing protective immunity against systemic pathogens. Upon secondary infection, these long-lived...
4.
Doan T, Forward T, Schafer J, Lucas E, Fleming I, Uecker-Martin A, et al.
NPJ Vaccines
. 2024 Mar;
9(1):66.
PMID: 38514656
Antigens from viruses or immunizations can persist or are archived in lymph node stromal cells such as lymphatic endothelial cells (LEC) and fibroblastic reticular cells (FRC). Here, we find that,...
5.
Sjaastad F, Huggins M, Lucas E, Skon-Hegg C, Swanson W, Martin M, et al.
J Immunol
. 2022 Nov;
209(11):2149-2159.
PMID: 36426978
Successful vaccination strategies offer the potential for lifelong immunity against infectious diseases and cancer. There has been increased attention regarding the limited translation of some preclinical findings generated using specific...
6.
Schafer J, Lucas E, Dzieciatkowska M, Forward T, Tamburini B
J Biol Chem
. 2022 Nov;
298(12):102694.
PMID: 36375639
Lymphatic endothelial cells (LECs) comprise lymphatic capillaries and vessels that guide immune cells to lymph nodes (LNs) and form the subcapsular sinus and cortical and medullary lymphatic structures of the...
7.
Whitesell J, Lindsay R, Olivas-Corral J, Yannacone S, Schoenbach M, Lucas E, et al.
Front Immunol
. 2022 Feb;
13:814203.
PMID: 35145521
T cells and B cells have been identified in human and murine islets, but the phenotype and role of islet lymphocytes is unknown. Resident immune populations set the stage for...
8.
Carpentier K, Sheridan R, Lucas C, Davenport B, Li F, Lucas E, et al.
EMBO J
. 2021 Oct;
40(22):e108966.
PMID: 34618370
Viremia in the vertebrate host is a major determinant of arboviral reservoir competency, transmission efficiency, and disease severity. However, immune mechanisms that control arboviral viremia are poorly defined. Here, we...
9.
Walsh S, Sheridan R, Lucas E, Doan T, Ware B, Schafer J, et al.
Elife
. 2021 Apr;
10.
PMID: 33843587
The detection of foreign antigens in vivo has relied on fluorescent conjugation or indirect read-outs such as antigen presentation. In our studies, we found that these widely used techniques had...
10.
Lucas E, Schafer J, Matsuda J, Kraus M, Burchill M, Tamburini B
Cell Rep
. 2020 Oct;
33(2):108258.
PMID: 33053342
Although the function of the extracellular region of programmed death ligand 1 (PD-L1) through its interactions with PD-1 on T cells is well studied, little is understood regarding the intracellular...