Erik Verschueren
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Explore the profile of Erik Verschueren including associated specialties, affiliations and a list of published articles.
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49
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2317
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Recent Articles
1.
Steiert B, Andersen S, McCaslin P, Elwell C, Faris R, Tijerina X, et al.
bioRxiv
. 2024 May;
PMID: 38712050
(.), the leading cause of bacterial sexually transmitted infections, employs a type III secretion system (T3SS) to translocate two classes of effectors, inclusion membrane proteins and conventional T3SS (cT3SS) effectors,...
2.
Chiu C, Li C, Verschueren E, Wen R, Zhang D, Gordon C, et al.
Int J Mol Sci
. 2023 Apr;
24(7).
PMID: 37047232
Increased expression of NUSAP1 has been identified as a robust prognostic biomarker in prostate cancer and other malignancies. We have previously shown that NUSAP1 is positively regulated by E2F1 and...
3.
Calses P, Pham V, Guarnaccia A, Choi M, Verschueren E, Bakker S, et al.
Mol Cell Proteomics
. 2023 Jan;
22(2):100496.
PMID: 36640924
Transcriptional enhanced associate domain family members 1 to 4 (TEADs) are a family of four transcription factors and the major transcriptional effectors of the Hippo pathway. In order to activate...
4.
Kohler D, Tsai T, Verschueren E, Huang T, Hinkle T, Phu L, et al.
Mol Cell Proteomics
. 2022 Dec;
22(1):100477.
PMID: 36496144
Liquid chromatography coupled with bottom-up mass spectrometry (LC-MS/MS)-based proteomics is increasingly used to detect changes in posttranslational modifications (PTMs) in samples from different conditions. Analysis of data from such experiments...
5.
Johnson J, Crosby D, Hultquist J, Kurland A, Adhikary P, Li D, et al.
Cell Rep
. 2022 Apr;
39(2):110690.
PMID: 35417684
Viruses must effectively remodel host cellular pathways to replicate and evade immune defenses, and they must do so with limited genomic coding capacity. Targeting post-translational modification (PTM) pathways provides a...
6.
Stormo A, Shavarebi F, Fitzgibbon M, Earley E, Ahrendt H, Lum L, et al.
J Cell Biol
. 2022 Mar;
221(4).
PMID: 35266954
Missense mutations in leucine-rich repeat kinase 2 (LRRK2) are the most common cause of familial Parkinson's disease (PD); however, pathways regulating LRRK2 subcellular localization, function, and turnover are not fully...
7.
Venkatanarayan A, Liang J, Yen I, Shanahan F, Haley B, Phu L, et al.
Cell Rep
. 2022 Feb;
38(6):110351.
PMID: 35139374
KRAS, which is mutated in ∼30% of all cancers, activates the RAF-MEK-ERK signaling cascade. CRAF is required for growth of KRAS mutant lung tumors, but the requirement for CRAF kinase...
8.
Astarita J, Keerthivasan S, Husain B, Senbabaoglu Y, Verschueren E, Gierke S, et al.
PLoS One
. 2021 Dec;
16(12):e0260800.
PMID: 34879110
The cancer-associated fibroblast (CAF) marker podoplanin (PDPN) is generally correlated with poor clinical outcomes in cancer patients and thus represents a promising therapeutic target. Despite its biomedical relevance, basic aspects...
9.
Li Q, Wong W, Birnberg A, Chakrabarti A, Yang X, Choy D, et al.
BMC Pulm Med
. 2021 Sep;
21(1):301.
PMID: 34556083
Background: Chronic obstructive pulmonary disease (COPD) exacerbations are heterogenous and profoundly impact the disease trajectory. Bioactive lipid lysophosphatidic acid (LPA) has been implicated in airway inflammation but the significance of...
10.
Keerthivasan S, Senbabaoglu Y, Martinez-Martin N, Husain B, Verschueren E, Wong A, et al.
Immunity
. 2021 Jul;
54(7):1511-1526.e8.
PMID: 34260887
Myeloid cells encounter stromal cells and their matrix determinants on a continual basis during their residence in any given organ. Here, we examined the impact of the collagen receptor LAIR1...