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Erik Dassi

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Articles 56
Citations 1441
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Recent Articles
1.
Di Leva F, Arnoldi M, Santarelli S, Massonot M, Lemee M, Bon C, et al.
Mol Ther . 2025 Jan; 33(3):1180-1196. PMID: 39741407
Loss-of-function mutations in the chromodomain helicase DNA-binding 8 (CHD8) gene are strongly associated with autism spectrum disorders (ASDs). Indeed, the reduction of CHD8 causes transcriptional, epigenetic, and cellular phenotypic changes...
2.
Bellina A, Malfatti M, Salgado G, Fleming A, Antoniali G, Othman Z, et al.
Proc Natl Acad Sci U S A . 2024 Nov; 121(46):e2317861121. PMID: 39495925
In the last decade, several novel functions of the mammalian Apurinic/Apyrimidinic Endodeoxyribonuclease 1 (APE1) have been discovered, going far beyond its canonical function as DNA repair enzyme and unveiling its...
3.
Destefanis E, Sighel D, Dalfovo D, Gilmozzi R, Broso F, Cappannini A, et al.
NAR Cancer . 2024 Oct; 6(4):zcae040. PMID: 39411658
N-Methyladenosine (mA) is the most abundant internal modification in mRNAs. Despite accumulating evidence for the profound impact of mA on cancer biology, there are conflicting reports that alterations in genes...
4.
Aguilo F, Dassi E
NAR Cancer . 2024 Jul; 6(3):zcae031. PMID: 39045152
No abstract available.
5.
Morandell J, Monziani A, Lazioli M, Donzel D, Doring J, Oss Pegorar C, et al.
Mol Ther Nucleic Acids . 2024 Jul; 35(3):102234. PMID: 38974999
Circular RNA (circRNA) molecules have critical functions during brain development and in brain-related disorders. Here, we identified and validated a circRNA, , stemming from the Huntington's disease (HD) gene locus...
6.
Cammas A, Desprairies A, Dassi E, Millevoi S
NAR Cancer . 2024 Jun; 6(2):zcae025. PMID: 38828391
Translational reprogramming in response to oncogenic signaling or microenvironmental stress factors shapes the proteome of cancer cells, enabling adaptation and phenotypic changes underlying cell plasticity, tumor progression and response to...
7.
Alaimo A, Genovesi S, Annesi N, De Felice D, Subedi S, Macchia A, et al.
EMBO J . 2024 Feb; 43(5):780-805. PMID: 38316991
Inflammation is a common condition of prostate tissue, whose impact on carcinogenesis is highly debated. Microbial colonization is a well-documented cause of a small percentage of prostatitis cases, but it...
8.
Ayyildiz D, Bergonzoni G, Monziani A, Tripathi T, Doring J, Kerschbamer E, et al.
PLoS Genet . 2023 Oct; 19(10):e1010988. PMID: 37831730
Alternative splicing (AS) appears to be altered in Huntington's disease (HD), but its significance for early, pre-symptomatic disease stages has not been inspected. Here, taking advantage of Htt CAG knock-in...
9.
Salvati E, Lewinska A, Dassi E, Wnuk M, DAgostino V
Front Oncol . 2023 Jul; 13:1222883. PMID: 37404766
No abstract available.
10.
Smurova K, Damizia M, Irene C, Stancari S, Berto G, Perticari G, et al.
Nat Commun . 2023 Jun; 14(1):3172. PMID: 37263996
Kinetochores assemble on centromeres via histone H3 variant CENP-A and low levels of centromere transcripts (cenRNAs). The latter are ensured by the downregulation of RNA polymerase II (RNAPII) activity, and...