Erica Shefler
Overview
Explore the profile of Erica Shefler including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
6700
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0
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Recent Articles
1.
McFadden D, Papagiannakopoulos T, Taylor-Weiner A, Stewart C, Carter S, Cibulskis K, et al.
Cell
. 2014 Mar;
156(6):1298-1311.
PMID: 24630729
Small cell lung carcinoma (SCLC) is a highly lethal, smoking-associated cancer with few known targetable genetic alterations. Using genome sequencing, we characterized the somatic evolution of a genetically engineered mouse...
2.
Francis J, Kiezun A, Ramos A, Serra S, Pedamallu C, Qian Z, et al.
Nat Genet
. 2013 Nov;
45(12):1483-6.
PMID: 24185511
The diagnosed incidence of small intestine neuroendocrine tumors (SI-NETs) is increasing, and the underlying genomic mechanisms have not yet been defined. Using exome- and genome-sequence analysis of SI-NETs, we identified...
3.
Lawrence M, Stojanov P, Polak P, Kryukov G, Cibulskis K, Sivachenko A, et al.
Nature
. 2013 Jun;
499(7457):214-218.
PMID: 23770567
Major international projects are underway that are aimed at creating a comprehensive catalogue of all the genes responsible for the initiation and progression of cancer. These studies involve the sequencing...
4.
Dulak A, Stojanov P, Peng S, Lawrence M, Fox C, Stewart C, et al.
Nat Genet
. 2013 Mar;
45(5):478-86.
PMID: 23525077
The incidence of esophageal adenocarcinoma (EAC) has risen 600% over the last 30 years. With a 5-year survival rate of ~15%, the identification of new therapeutic targets for EAC is...
5.
Pugh T, Morozova O, Attiyeh E, Asgharzadeh S, Wei J, Auclair D, et al.
Nat Genet
. 2013 Jan;
45(3):279-84.
PMID: 23334666
Neuroblastoma is a malignancy of the developing sympathetic nervous system that often presents with widespread metastatic disease, resulting in survival rates of less than 50%. To determine the spectrum of...
6.
Pugh T, Weeraratne S, Archer T, Pomeranz Krummel D, Auclair D, Bochicchio J, et al.
Nature
. 2012 Jul;
488(7409):106-10.
PMID: 22820256
Medulloblastomas are the most common malignant brain tumours in children. Identifying and understanding the genetic events that drive these tumours is critical for the development of more effective diagnostic, prognostic...
7.
Wang L, Lawrence M, Wan Y, Stojanov P, Sougnez C, Stevenson K, et al.
N Engl J Med
. 2011 Dec;
365(26):2497-506.
PMID: 22150006
Background: The somatic genetic basis of chronic lymphocytic leukemia, a common and clinically heterogeneous leukemia occurring in adults, remains poorly understood. Methods: We obtained DNA samples from leukemia cells in...
8.
Stransky N, Egloff A, Tward A, Kostic A, Cibulskis K, Sivachenko A, et al.
Science
. 2011 Jul;
333(6046):1157-60.
PMID: 21798893
Head and neck squamous cell carcinoma (HNSCC) is a common, morbid, and frequently lethal malignancy. To uncover its mutational spectrum, we analyzed whole-exome sequencing data from 74 tumor-normal pairs. The...