Eric R Gremmer
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Explore the profile of Eric R Gremmer including associated specialties, affiliations and a list of published articles.
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32
Citations
512
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Recent Articles
1.
Bovee T, Heusinkveld H, Dodd S, Peijnenburg A, Rijkers D, Blokland M, et al.
Food Chem Toxicol
. 2024 Jan;
184:114432.
PMID: 38176580
Background: Human exposure to pesticides is being associated with feminisation for which a decrease of the anogenital distance (AGD) is a sensitive endpoint. Dose addition for the cumulative risk assessment...
2.
Braakhuis H, Gremmer E, Bannuscher A, Drasler B, Keshavan S, Rothen-Rutishauser B, et al.
NanoImpact
. 2023 May;
31:100466.
PMID: 37209722
Background: The establishment of reliable and robust in vitro models for hazard assessment, a prerequisite for moving away from animal testing, requires the evaluation of model transferability and reproducibility. Lung...
3.
Bannuscher A, Schmid O, Drasler B, Rohrbasser A, Braakhuis H, Meldrum K, et al.
NanoImpact
. 2022 Nov;
28:100439.
PMID: 36402283
Air-liquid interface (ALI) lung cell models cultured on permeable transwell inserts are increasingly used for respiratory hazard assessment requiring controlled aerosolization and deposition of any material on ALI cells. The...
4.
Tulen C, Duistermaat E, Cremers J, Klerx W, Fokkens P, Weibolt N, et al.
Cells
. 2022 Nov;
11(21).
PMID: 36359877
Chronic obstructive pulmonary disease (COPD) is a devastating lung disease primarily caused by exposure to cigarette smoke (CS). During the pyrolysis and combustion of tobacco, reactive aldehydes such as acetaldehyde,...
5.
van der Ven L, Van Ommeren P, Zwart E, Gremmer E, Hodemaekers H, Heusinkveld H, et al.
Environ Health Perspect
. 2022 Apr;
130(4):47003.
PMID: 35394809
Background: Humans are exposed to combinations of chemicals. In cumulative risk assessment (CRA), regulatory bodies such as the European Food Safety Authority consider dose addition as a default and sufficiently...
6.
He R, Braakhuis H, Vandebriel R, Staal Y, Gremmer E, Fokkens P, et al.
J Aerosol Sci
. 2021 Mar;
153:105703.
PMID: 33658726
Inhalation exposure to environmental and occupational aerosol contaminants is associated with many respiratory health problems. To realistically mimic long-term inhalation exposure for toxicity testing, lung epithelial cells need to maintained...
7.
Braakhuis H, He R, Vandebriel R, Gremmer E, Zwart E, Vermeulen J, et al.
J Vis Exp
. 2020 Jun;
(159).
PMID: 32478724
For toxicity testing of airborne particles, air-liquid interface (ALI) exposure systems have been developed for in vitro tests in order to mimic realistic exposure conditions. This puts specific demands on...
8.
Medina-Reyes E, Delgado-Buenrostro N, Leseman D, Deciga-Alcaraz A, He R, Gremmer E, et al.
Toxicol In Vitro
. 2020 Feb;
65:104798.
PMID: 32084520
Air Liquid Interface (ALI) system has emerged as a useful tool for toxicity evaluation of nanomaterials related to inhalation since the system mimics the aerosol exposure. We compared the biological...
9.
Zoupa M, Zwart E, Gremmer E, Nugraha A, Compeer S, Slob W, et al.
Food Chem Toxicol
. 2020 Jan;
137:111117.
PMID: 31927004
A challenge in cumulative risk assessment is to model hazard of mixtures. EFSA proposed to only combine chemicals linked to a defined endpoint, in so-called cumulative assessment groups, and use...
10.
Giannakou C, Aimonen K, van Bloois L, Catalan J, Geertsma R, Gremmer E, et al.
Nanomedicine (Lond)
. 2019 May;
14(10):1231-1246.
PMID: 31124759
Nanomaterials and nanomedicinal products tend to interfere with various commonly used assays, including regulatory required endotoxin detection methods for medicines. We developed a method to quantify endotoxin levels that is...