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Eric P Zorrilla

Explore the profile of Eric P Zorrilla including associated specialties, affiliations and a list of published articles. Areas
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Articles 99
Citations 5080
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Recent Articles
1.
Cruz B, Vozella V, Borgonetti V, Bullard R, Bianchi P, Kirson D, et al.
Mol Psychiatry . 2024 Mar; 29(9):2611-2621. PMID: 38509197
Post-traumatic stress disorder (PTSD) and alcohol use disorder (AUD) are often comorbid. Few treatments exist to reduce comorbid PTSD/AUD. Elucidating the mechanisms underlying their comorbidity could reveal new avenues for...
2.
Bertotto L, Lampson-Stixrud D, Sinha A, Rohani N, Myer I, Zorrilla E
Cells . 2024 Feb; 13(4. PMID: 38391934
Alcohol use disorder (AUD) requires new neurobiological targets. Problematic drinking involves underactive indirect pathway medium spiny neurons (iMSNs) that subserve adaptive behavioral selection vs. overactive direct pathway MSNs (dMSNs) that...
3.
Borgonetti V, Cruz B, Vozella V, Khom S, Steinman M, Bullard R, et al.
Cells . 2023 Aug; 12(15). PMID: 37566022
Alcohol use disorder (AUD) and anxiety disorders are frequently comorbid and share dysregulated neuroimmune-related pathways. Here, we used our established rat model of comorbid post-traumatic stress disorder (PTSD)/AUD to characterize...
4.
Vozella V, Cruz B, Feldman H, Bullard R, Bianchi P, Natividad L, et al.
Br J Pharmacol . 2023 Jul; 180(24):3130-3145. PMID: 37488777
Background And Purpose: The endocannabinoid (eCB) system plays an important homeostatic role in the regulation of stress circuits and has emerged as a therapeutic target to treat stress disorders and...
5.
Cruz B, Vozella V, Carper B, Xu J, Kirson D, Hirsch S, et al.
Neuropsychopharmacology . 2022 Nov; 48(8):1144-1154. PMID: 36396784
Post-traumatic stress disorder (PTSD) leads to enhanced alcohol drinking and development of alcohol use disorder (AUD). Identifying shared neural mechanisms might help discover new therapies for PTSD/AUD. Here, we employed...
6.
Kirson D, Spierling Bagsic S, Murphy J, Chang H, Vlkolinsky R, Pucci S, et al.
Neuropharmacology . 2022 Feb; 208:108980. PMID: 35122838
Compulsive eating is an overlapping construct with binge eating that shares many characteristics with substance use disorders. Compulsive eating may impact millions of Americans; presenting in some cases of binge...
7.
Laque A, Wagner G, Matzeu A, De Ness G, Kerr T, Carroll A, et al.
Br J Pharmacol . 2022 Jan; 179(11):2589-2609. PMID: 35023154
Background And Purpose: 'Food addiction' is the subject of intense public and research interest. However, this nosology based on neurobehavioural similarities among obese individuals, patients with eating disorders and those...
8.
Kirson D, Steinman M, Wolfe S, Spierling Bagsic S, Bajo M, Sureshchandra S, et al.
J Neurosci Res . 2021 Oct; 99(12):3354-3372. PMID: 34687080
Alcohol use disorder (AUD) and affective disorders are frequently comorbid and share underlying mechanisms that could be targets for comprehensive treatment. Post-traumatic stress disorder (PTSD) has high comorbidity with AUD,...
9.
Serafine K, ODell L, Zorrilla E
Neuropharmacology . 2021 Apr; 196:108556. PMID: 33862029
Highly palatable foods and substance of abuse have intersecting neurobiological, metabolic and behavioral effects relevant for understanding vulnerability to conditions related to food (e.g., obesity, binge eating disorder) and drug...
10.
Vozella V, Cruz B, Natividad L, Benvenuti F, Cannella N, Edwards S, et al.
Int J Mol Sci . 2021 Apr; 22(6). PMID: 33803557
Marchigian Sardinian alcohol-preferring (msP) rats serve as a unique model of heightened alcohol preference and anxiety disorders. Their innate enhanced stress and poor stress-coping strategies are driven by a genetic...