Eric P Zorrilla
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Explore the profile of Eric P Zorrilla including associated specialties, affiliations and a list of published articles.
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99
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5080
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Recent Articles
11.
Okhuarobo A, Bolton J, Igbe I, Zorrilla E, Baram T, Contet C
Neurobiol Stress
. 2020 Dec;
13:100269.
PMID: 33344722
Childhood adversity increases vulnerability to alcohol use disorders and preclinical models are needed to investigate the underlying neurobiological mechanisms. The present study modeled early-life adversity by rearing male and female...
12.
Steinman M, Kirson D, Wolfe S, Khom S, DAmbrosio S, Spierling Bagsic S, et al.
Mol Psychiatry
. 2020 Oct;
26(7):3093-3107.
PMID: 33087855
Alcohol use disorder (AUD) and anxiety disorders are frequently comorbid and share mechanisms that could be therapeutic targets. To facilitate mechanistic studies, we adapted an inhibitory avoidance-based "2-hit" rat model...
13.
Spierling S, de Guglielmo G, Kirson D, Kreisler A, Roberto M, George O, et al.
Neuropsychopharmacology
. 2019 Oct;
45(4):579-588.
PMID: 31593982
Compulsive eating characterizes many binge-related eating disorders, yet its neurobiological basis is poorly understood. The insular cortex subserves visceral-emotional functions, including taste processing, and is implicated in drug craving and...
14.
Zorrilla E, Koob G
Front Behav Neurosci
. 2019 Sep;
13:188.
PMID: 31501652
[This corrects the article DOI: 10.3389/fnbeh.2019.00136.].
15.
Zorrilla E, Koob G
Front Behav Neurosci
. 2019 Jul;
13:136.
PMID: 31293401
Negative urgency is a unique dimension of impulsivity that involves acting rashly when in extreme distress and impairments in inhibitory control. It has been hypothesized to derive from stress that...
16.
Serrano A, Pavon F, Buczynski M, Schlosburg J, Natividad L, Polis I, et al.
Neuropsychopharmacology
. 2018 May;
43(9):1840-1850.
PMID: 29748627
Negative emotional states that are associated with excessive alcohol intake, particularly anxiety-like states, have been linked to opponent processes in the central nucleus of the amygdala (CeA), affecting stress-related transmitters...
17.
Spierling S, Kreisler A, Williams C, Fang S, Pucci S, Kines K, et al.
Physiol Behav
. 2018 Apr;
192:3-16.
PMID: 29654812
Compulsive binge eating is a hallmark of binge eating disorder and bulimia nervosa and is implicated in some obesity cases. Eating disorders are sexually dimorphic, with females more often affected...
18.
Logrip M, Walker J, Ayanwuyi L, Sabino V, Ciccocioppo R, Koob G, et al.
Front Psychiatry
. 2018 Mar;
9:28.
PMID: 29497387
Alcoholism is a pervasive societal problem, yet available pharmacotherapies fail to treat most sufferers. The type 1 corticotropin-releasing factor (CRF) receptor has received much attention for its putative role in...
19.
Rupprecht L, Kreisler A, Spierling S, de Guglielmo G, Kallupi M, George O, et al.
Psychopharmacology (Berl)
. 2018 Jan;
235(4):1131-1140.
PMID: 29354872
Rationale: The ability of nicotine to suppress body weight is cited as a factor impacting smoking initiation and the failure to quit. Self-administered nicotine in male rats suppresses weight independent...
20.
Roberto M, Spierling S, Kirson D, Zorrilla E
Int Rev Neurobiol
. 2017 Oct;
136:5-51.
PMID: 29056155
Drug addiction is a complex disorder that is characterized by compulsivity to seek and take the drug, loss of control in limiting intake of the drug, and emergence of a...