Eric O Williams
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Explore the profile of Eric O Williams including associated specialties, affiliations and a list of published articles.
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13
Citations
562
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Recent Articles
1.
Martinez A, Chung A, Huang S, Bisogni A, Lin Y, Cao Y, et al.
iScience
. 2023 Nov;
26(11):108220.
PMID: 37965156
The mouse olfactory system regenerates constantly throughout life. While genes critical for the initial projection of olfactory sensory neurons (OSNs) to the olfactory bulb have been identified, what genes are...
2.
Tominaga K, Tominaga N, Williams E, Rufibach L, Schowel V, Spuler S, et al.
iScience
. 2022 Jan;
25(1):103667.
PMID: 35028538
Dysferlinopathies are muscular dystrophies caused by recessive loss-of-function mutations in dysferlin (), a membrane protein involved in skeletal muscle membrane repair. We describe a cell-based assay in which human DYSF...
3.
Das A, Huang G, Bonkowski M, Longchamp A, Li C, Schultz M, et al.
Cell
. 2019 Feb;
176(4):944-945.
PMID: 30735637
No abstract available.
4.
Bisogni A, Ghazanfar S, Williams E, Marsh H, Yang J, Lin D
Elife
. 2018 Dec;
7.
PMID: 30547884
The delta-protocadherins (δ-Pcdhs) play key roles in neural development, and expression studies suggest they are expressed in combination within neurons. The extent of this combinatorial diversity, and how these combinations...
5.
Das A, Huang G, Bonkowski M, Longchamp A, Li C, Schultz M, et al.
Cell
. 2018 Mar;
173(1):74-89.e20.
PMID: 29570999
A decline in capillary density and blood flow with age is a major cause of mortality and morbidity. Understanding why this occurs is key to future gains in human health....
6.
Williams E, Taylor A, Bell E, Lim R, Kim D, Guarente L
Cell Rep
. 2016 Oct;
17(3):809-820.
PMID: 27732856
The enhancer landscape is dramatically restructured as naive preimplantation epiblasts transition to the post-implantation state of primed pluripotency. A key factor in this process is Otx2, which is upregulated during...
7.
Bell E, Nagamori I, Williams E, Del Rosario A, Bryson B, Watson N, et al.
Development
. 2014 Aug;
141(18):3495-504.
PMID: 25142464
Sirtuins are NAD(+)-dependent deacylases that regulate numerous biological processes in response to the environment. SirT1 is the mammalian ortholog of yeast Sir2, and is involved in many metabolic pathways in...
8.
Simic P, Williams E, Bell E, Gong J, Bonkowski M, Guarente L
Cell Rep
. 2013 Apr;
3(4):1175-86.
PMID: 23583181
The epithelial-to-mesenchymal transition (EMT) is important for the development of cancer metastases and organ fibrosis, conditions prevalent in aging. Because sirtuins affect the pathology of aging, we tested the effect...
9.
Williams E, Sickles H, Dooley A, Palumbos S, Bisogni A, Lin D
Front Neural Circuits
. 2011 Sep;
5:9.
PMID: 21897809
Olfactory sensory neurons (OSNs) are thought to use activity-dependent and independent mechanisms to regulate the expression of axon guidance genes. However, defining the molecular mechanisms that underlie activity-dependent OSN guidance...
10.
Boston-Howes W, Williams E, Bogush A, Scolere M, Pasinelli P, Trotti D
Exp Neurol
. 2008 Jul;
213(1):229-37.
PMID: 18625223
Synaptic accumulation of glutamate causes neuronal death in many neurodegenerative pathologies including amyotrophic lateral sclerosis. Drugs capable of increasing glutamate uptake could therefore be therapeutically effective. We screened in a...