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Eric M Pridgen

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Articles 15
Citations 787
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Recent Articles
1.
Prat D, Sourugeon Y, Haghverdian B, Pridgen E, Lee W, Wapner K, et al.
J Foot Ankle Surg . 2023 May; 62(5):855-861. PMID: 37220866
"Cup-shaped power reamers" and "flat cuts" (FC) are common joint preparation techniques in first metatarsophalangeal (MTP) joint arthrodesis. However, the third option of an "in situ" (IS) technique has rarely...
2.
Prat D, Haghverdian B, Pridgen E, Lee W, Wapner K, Chao W, et al.
Arch Orthop Trauma Surg . 2022 Jan; 143(4):1799-1807. PMID: 35092466
Background: The most common indications for revision of first metatarsophalangeal joint (MTPJ) arthrodesis are symptomatic failures of prior arthrodesis, failed hallux valgus correction, and failed MTPJ arthroplasty implants. However, the...
3.
DeBaun M, Williams J, Bennett C, Pridgen E, Tamurian R, Amanatullah D
Knee . 2019 Aug; 26(5):1020-1025. PMID: 31405629
Purpose: Bone tumors are common in the distal femur and often treated with intralesional curettage. The optimal method of stabilization of large distal femoral defects after curettage remains unclear. The...
4.
Mooney J, Pridgen E, Manasherob R, Suh G, Blackwell H, Barron A, et al.
J Orthop Res . 2018 Apr; 36(9):2331-2339. PMID: 29663554
Periprosthetic joint infection (PJI) is a common complication after total joint arthroplasty leading to severe morbidity and mortality. With an aging population and increasing prevalence of total joint replacement procedures,...
5.
Pridgen E, Alexis F, Farokhzad O
Expert Opin Drug Deliv . 2015 Mar; 12(9):1459-73. PMID: 25813361
Introduction: Many therapeutics are limited to parenteral administration. Oral administration is a desirable alternative because of the convenience and increased compliance by patients, especially for chronic diseases that require frequent...
6.
Pridgen E, Alexis F, Farokhzad O
Clin Gastroenterol Hepatol . 2014 Jul; 12(10):1605-10. PMID: 24981782
Biologics increasingly are being used for the treatment of many diseases. These treatments typically require repeated doses administered by injection. Alternate routes of administration, particularly oral, are considered favorable because...
7.
Pridgen E, Alexis F, Kuo T, Levy-Nissenbaum E, Karnik R, Blumberg R, et al.
Sci Transl Med . 2013 Nov; 5(213):213ra167. PMID: 24285486
Nanoparticles are poised to have a tremendous impact on the treatment of many diseases, but their broad application is limited because currently they can only be administered by parenteral methods....
8.
Valencia P, Pridgen E, Rhee M, Langer R, Farokhzad O, Karnik R
ACS Nano . 2013 Nov; 7(12):10671-80. PMID: 24215426
Taking a nanoparticle (NP) from discovery to clinical translation has been slow compared to small molecules, in part by the lack of systems that enable their precise engineering and rapid...
9.
Xu X, Xie K, Zhang X, Pridgen E, Park G, Cui D, et al.
Proc Natl Acad Sci U S A . 2013 Oct; 110(46):18638-43. PMID: 24167294
Cisplatin and other DNA-damaging chemotherapeutics are widely used to treat a broad spectrum of malignancies. However, their application is limited by both intrinsic and acquired chemoresistance. Most mutations that result...
10.
Johnstone T, Kulak N, Pridgen E, Farokhzad O, Langer R, Lippard S
ACS Nano . 2013 May; 7(7):5675-83. PMID: 23697579
Nanoparticle (NP) therapeutics have the potential to significantly alter the in vivo biological properties of the pharmaceutically active agents that they carry. Here we describe the development of a polymeric...