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Eric L Dane

Explore the profile of Eric L Dane including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 667
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Recent Articles
1.
Mandal S, Melo M, Gordiichuk P, Acharya S, Poh Y, Li N, et al.
bioRxiv . 2023 Oct; PMID: 37873483
Cytotoxic T lymphocytes (CTLs) carry out immunosurveillance by scanning target cells of diverse physical properties for the presence of antigens. While the recognition of cognate antigen by the T cell...
2.
Kataria S, Qi J, Lin C, Li Z, Dane E, Iyer A, et al.
ACS Nano . 2023 Sep; 17(18):17908-17919. PMID: 37676036
Only a minority of patients respond positively to cancer immunotherapy, and addressing this variability is an active area of immunotherapy research. Infiltration of tumors by immune cells is one of...
3.
Dane E, Belessiotis-Richards A, Backlund C, Wang J, Hidaka K, Milling L, et al.
Nat Mater . 2022 May; 21(6):710-720. PMID: 35606429
Activation of the innate immune STimulator of INterferon Genes (STING) pathway potentiates antitumour immunity, but systemic delivery of STING agonists to tumours is challenging. We conjugated STING-activating cyclic dinucleotides (CDNs)...
4.
Irvine D, Dane E
Nat Rev Immunol . 2020 Feb; 20(5):321-334. PMID: 32005979
Therapeutic targeting of the immune system in cancer is now a clinical reality and marked successes have been achieved, most notably through the use of checkpoint blockade antibodies and chimeric...
5.
Tokatlian T, Read B, Jones C, Kulp D, Menis S, Chang J, et al.
Science . 2018 Dec; 363(6427):649-654. PMID: 30573546
In vaccine design, antigens are often arrayed in a multivalent nanoparticle form, but in vivo mechanisms underlying the enhanced immunity elicited by such vaccines remain poorly understood. We compared the...
6.
Xiao R, Dane E, Zeng J, McKnight C, Grinstaff M
J Am Chem Soc . 2017 Sep; 139(40):14217-14223. PMID: 28902504
The design and synthesis of amide-linked saccharide oligomers and polymers, which are predisposed to fold into specific ordered secondary structures, is of significant interest. Herein, right-handed helical poly amido-saccharides (PASs)...
7.
Chin S, Lu Q, Dane E, Dominguez L, McKnight C, Straub J, et al.
J Am Chem Soc . 2016 Apr; 138(20):6532-40. PMID: 27119983
Poly-amido-saccharides (PAS) are carbohydrate-based, enantiopure synthetic polymers in which sugar repeat units are joined by amide linkages. This unique and relatively rigid pyranose backbone contributes to their defined helical secondary...
8.
Dane E, Irvine D
Nat Biotechnol . 2015 Nov; 33(11):1146-8. PMID: 26544144
No abstract available.
9.
Stidham S, Chin S, Dane E, Grinstaff M
J Am Chem Soc . 2014 Jun; 136(27):9544-7. PMID: 24949521
The synthesis of novel carbohydrate-based polymers allows the structure to be tailored at the monomer level for a specific property and expands the range of available structures beyond those found...
10.
Ghobril C, Heinrich B, Dane E, Grinstaff M
ACS Macro Lett . 2014 May; 3(4):359-363. PMID: 24804154
The first synthesis of enantiopure glucose octyl ether polyamido-saccharides (GOE-PAS) with a defined molecular weight and narrow dispersity is reported using a controlled anionic ring-opening polymerization of a glucose-derived β-lactam...