Eric Keil
Overview
Explore the profile of Eric Keil including associated specialties, affiliations and a list of published articles.
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Articles
5
Citations
113
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0
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Recent Articles
1.
Aparicio-Siegmund S, Sommer J, Monhasery N, Schwanbeck R, Keil E, Finkenstadt D, et al.
Oncotarget
. 2014 Apr;
5(8):2131-48.
PMID: 24742922
The Janus kinase / signal transducer and activator of transcription (Jak/STAT) pathway can be activated by many different cytokines, among them all members of the Interleukin (IL-)6 family. Dysregulation of...
2.
Keil E, Finkenstadt D, Wufka C, Trilling M, Liebfried P, Strobl B, et al.
Blood
. 2013 Oct;
123(4):520-9.
PMID: 24169825
Janus kinases (Jak) play essential roles in cytokine and growth factor signaling. Conventional gene targeting of Jak2, creating a null allele, leads to a block in definitive erythropoiesis as a...
3.
Schmidt S, Ebel S, Keil E, Woite C, Ernst J, Benzin A, et al.
PLoS One
. 2013 May;
8(5):e63301.
PMID: 23675474
Tryptophan is an essential amino acid for human beings as well as for some microorganisms. In human cells the interferon-γ (IFN-γ) inducible enzyme indoleamine 2,3-dioxygenase (IDO) reduces local tryptophan levels...
4.
Ueffing N, Schuster M, Keil E, Schulze-Osthoff K, Schmitz I
Blood
. 2008 May;
112(3):690-8.
PMID: 18509086
Upon encounter with pathogens, T cells activate several defense mechanisms, one of which is the up-regulation of CD95 ligand (CD95L/FasL) which induces apoptosis in sensitive target cells. Despite expression of...
5.
Samraj A, Keil E, Ueffing N, Schulze-Osthoff K, Schmitz I
J Biol Chem
. 2006 Aug;
281(40):29652-9.
PMID: 16895904
The death receptor CD95 triggers apoptosis upon formation of a death-inducing signaling complex and the activation of caspase-8. Two types of CD95-mediated apoptosis have been distinguished that differ in their...