Eric Haugen
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Explore the profile of Eric Haugen including associated specialties, affiliations and a list of published articles.
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9982
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Recent Articles
11.
van der Harst P, van Setten J, Verweij N, Vogler G, Franke L, Maurano M, et al.
J Am Coll Cardiol
. 2016 Sep;
68(13):1435-1448.
PMID: 27659466
Background: Myocardial mass is a key determinant of cardiac muscle function and hypertrophy. Myocardial depolarization leading to cardiac muscle contraction is reflected by the amplitude and duration of the QRS...
12.
Kohen R, Tracy J, Haugen E, Cain K, Jarrett M, Heitkemper M
Biol Res Nurs
. 2016 Feb;
18(4):394-400.
PMID: 26912503
Alterations in serotonin signaling are suspected in the pathophysiology of irritable bowel syndrome (IBS). By modulating the extracellular reuptake of serotonin, the serotonin transporter (SERT) acts as a key regulator...
13.
Maurano M, Haugen E, Sandstrom R, Vierstra J, Shafer A, Kaul R, et al.
Nat Genet
. 2015 Dec;
48(1):101.
PMID: 26711113
No abstract available.
14.
Maurano M, Haugen E, Sandstrom R, Vierstra J, Shafer A, Kaul R, et al.
Nat Genet
. 2015 Oct;
47(12):1393-401.
PMID: 26502339
The function of human regulatory regions depends exquisitely on their local genomic environment and on cellular context, complicating experimental analysis of common disease- and trait-associated variants that localize within regulatory...
15.
Vierstra J, Rynes E, Sandstrom R, Zhang M, Canfield T, Hansen R, et al.
Science
. 2014 Nov;
346(6212):1007-12.
PMID: 25411453
To study the evolutionary dynamics of regulatory DNA, we mapped >1.3 million deoxyribonuclease I-hypersensitive sites (DHSs) in 45 mouse cell and tissue types, and systematically compared these with human DHS...
16.
Stergachis A, Neph S, Sandstrom R, Haugen E, Reynolds A, Zhang M, et al.
Nature
. 2014 Nov;
515(7527):365-70.
PMID: 25409825
The basic body plan and major physiological axes have been highly conserved during mammalian evolution, yet only a small fraction of the human genome sequence appears to be subject to...
17.
Yue F, Cheng Y, Breschi A, Vierstra J, Wu W, Ryba T, et al.
Nature
. 2014 Nov;
515(7527):355-64.
PMID: 25409824
The laboratory mouse shares the majority of its protein-coding genes with humans, making it the premier model organism in biomedical research, yet the two mammals differ in significant ways. To...
18.
Sullivan A, Arsovski A, Lempe J, Bubb K, Weirauch M, Sabo P, et al.
Cell Rep
. 2014 Sep;
8(6):2015-2030.
PMID: 25220462
Our understanding of gene regulation in plants is constrained by our limited knowledge of plant cis-regulatory DNA and its dynamics. We mapped DNase I hypersensitive sites (DHSs) in A. thaliana...
19.
Sandstrom R, Foret M, Grow D, Haugen E, Rhodes C, Cardona A, et al.
Sci Rep
. 2014 Jun;
4:5371.
PMID: 24947819
Histone 3 lysine 4 trimethylation (H3K4me3) is known to be associated with transcriptionally active or poised genes and required for postnatal neurogenesis within the subventricular zone (SVZ) in the rodent...
20.
Stergachis A, Haugen E, Shafer A, Fu W, Vernot B, Reynolds A, et al.
Science
. 2013 Dec;
342(6164):1367-72.
PMID: 24337295
Genomes contain both a genetic code specifying amino acids and a regulatory code specifying transcription factor (TF) recognition sequences. We used genomic deoxyribonuclease I footprinting to map nucleotide resolution TF...