Eric Boitier
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Explore the profile of Eric Boitier including associated specialties, affiliations and a list of published articles.
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23
Citations
229
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Recent Articles
1.
Tolaney S, Chan A, Petrakova K, Delaloge S, Campone M, Iwata H, et al.
J Clin Oncol
. 2023 Jun;
41(24):4014-4024.
PMID: 37348019
Purpose: Amcenestrant (oral selective estrogen receptor degrader) demonstrated promising safety and efficacy in earlier clinical studies for endocrine-resistant, estrogen receptor-positive/human epidermal growth factor receptor 2-negative (ER+/HER2-) advanced breast cancer (aBC)....
2.
Lopez-Longarela B, Morrison E, Tranter J, Chahman-Vos L, Leonard J, Gautier J, et al.
Anal Chem
. 2020 Jan;
92(4):3388-3395.
PMID: 31939284
Circulating microRNAs are biomarkers reported to be stable and translational across species. MicroRNA-122 (miR-122) is a hepatocyte-specific microRNA biomarker for drug-induced liver injury (DILI). We developed a single molecule, dynamic...
3.
Allanore Y, Distler O, Jagerschmidt A, Illiano S, Ledein L, Boitier E, et al.
Arthritis Rheumatol
. 2018 May;
70(10):1634-1643.
PMID: 29732731
Objective: Preclinical studies suggest a role for lysophosphatidic acid (LPA) in the pathogenesis of systemic sclerosis (SSc). We undertook this study to assess SAR100842, a potent selective oral antagonist of...
4.
Wolfinger R, Beedanagari S, Boitier E, Chen T, Couttet P, Ellinger-Ziegelbauer H, et al.
BMC Biotechnol
. 2018 Feb;
18(1):6.
PMID: 29391006
Background: Circulating microRNAs are undergoing exploratory use as safety biomarkers in drug development. Reverse transcription quantitative polymerase chain reaction (RT-qPCR) is one common approach used to quantitate levels of microRNAs...
5.
Veeranagouda Y, Leonard J, Gautier J, Boitier E
Methods Mol Biol
. 2017 Jul;
1641:349-378.
PMID: 28748475
Advanced sequencing technologies like next-generation sequencing (NGS) not only detect microRNAs (miRNAs) in biological samples but also facilitate de novo identification of miRNAs. Using an Ion Torrent's Ion Proton System,...
6.
Veeranagouda Y, Rival P, Prades C, Mariet C, Leonard J, Gautier J, et al.
PLoS One
. 2016 Oct;
11(10):e0164317.
PMID: 27695060
[This corrects the article DOI: 10.1371/journal.pone.0142708.].
7.
Thompson K, Boitier E, Chen T, Couttet P, Ellinger-Ziegelbauer H, Goetschy M, et al.
Toxicol Sci
. 2016 Sep;
154(1):115-125.
PMID: 27605421
Extracellular microRNAs (miRNAs) represent a promising new source of toxicity biomarkers that are sensitive indicators of site of tissue injury. In order to establish reliable approaches for use in biomarker...
8.
Gautier J, Zhou X, Yang Y, Gury T, Qu Z, Palazzi X, et al.
Toxicol Appl Pharmacol
. 2016 Apr;
303:1-10.
PMID: 27105553
Most studies to evaluate kidney safety biomarkers have been performed in rats. This study was conducted in Cynomolgus monkeys in order to evaluate the potential usefulness of novel biomarkers of...
9.
Veeranagouda Y, Rival P, Prades C, Mariet C, Leonard J, Gautier J, et al.
PLoS One
. 2015 Nov;
10(11):e0142708.
PMID: 26562842
MicroRNAs (miRNAs) present in tissues and biofluids are emerging as sensitive and specific safety biomarkers. MiRNAs have not been thoroughly described in M. fascicularis, an animal model used in pharmaceutical...
10.
Com E, Boitier E, Marchandeau J, Brandenburg A, Schroeder S, Hoffmann D, et al.
Toxicol Appl Pharmacol
. 2011 Nov;
258(1):124-33.
PMID: 22061828
Gentamicin is an aminoglycoside antibiotic, which induces renal tubular necrosis in rats. In the context of the European InnoMed PredTox project, transcriptomic and proteomic studies were performed to provide new...