Eric A Porsch
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Explore the profile of Eric A Porsch including associated specialties, affiliations and a list of published articles.
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Citations
268
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Recent Articles
1.
Morreale D, Porsch E, Kern B, St Geme 3rd J, Planet P
Nat Commun
. 2023 Jul;
14(1):4281.
PMID: 37460464
The bacterial genus Kingella includes two pathogenic species, namely Kingella kingae and Kingella negevensis, as well as strictly commensal species. Both K. kingae and K. negevensis secrete a toxin called...
2.
Maher J, Mendes R, Huynh H, Porsch E, St Geme Iii J, Yagupsky P, et al.
Pediatr Infect Dis J
. 2023 Feb;
42(3):206-211.
PMID: 36728824
Background: Improvements in blood culture techniques and molecular-based diagnostics have led to increased recognition of Kingella kingae as an invasive human pathogen causing bacteremia, septic arthritis, osteomyelitis and endocarditis in...
3.
Sacharok A, Porsch E, St Geme 3rd J
Infect Immun
. 2022 Dec;
91(1):e0033822.
PMID: 36537792
Kingella kingae is an emerging pathogen that has recently been identified as a leading cause of osteoarticular infections in young children. Colonization with K. kingae is common, with approximately 10%...
4.
Porsch E, Hernandez K, Morreale D, Montoya N, Yount T, St Geme 3rd J
Front Pediatr
. 2022 Oct;
10:1018054.
PMID: 36304526
is an emerging pediatric pathogen and is increasingly recognized as a leading etiology of septic arthritis, osteomyelitis, and bacteremia and an occasional cause of endocarditis in young children. The pathogenesis...
5.
Montoya N, Porsch E, Munoz V, Muszynski A, Vlach J, Hahn D, et al.
mBio
. 2022 Sep;
13(5):e0229522.
PMID: 36069736
Kingella kingae is a leading cause of bone and joint infections and other invasive diseases in young children. A key K. kingae virulence determinant is a secreted exopolysaccharide that mediates...
6.
Porsch E
Microorganisms
. 2022 May;
10(5).
PMID: 35630439
The emergence of as an important etiology of pediatric osteoarticular infections over the past three decades has led to significant research efforts focused on understanding the pathogenicity of this fastidious...
7.
Sacharok A, Porsch E, Yount T, Keenan O, St Geme 3rd J
PLoS Pathog
. 2022 Mar;
18(3):e1010440.
PMID: 35353876
The gram-negative bacterium Kingella kingae is a leading cause of osteoarticular infections in young children and initiates infection by colonizing the oropharynx. Adherence to respiratory epithelial cells represents an initial...
8.
Kadry N, Porsch E, Shen H, St Geme 3rd J
Proc Natl Acad Sci U S A
. 2021 Aug;
118(32).
PMID: 34344825
Nontypeable (NTHi) is a common cause of localized respiratory tract disease and results in significant morbidity. The pathogenesis of NTHi disease begins with nasopharyngeal colonization, and therefore, the prevention of...
9.
Fernandez-Calvet A, Euba B, Gil-Campillo C, Catalan-Moreno A, Moleres J, Marti S, et al.
mBio
. 2021 Jun;
12(3):e0078921.
PMID: 34154422
Genetic variants arising from within-patient evolution shed light on bacterial adaptation during chronic infection. Contingency loci generate high levels of genetic variation in bacterial genomes, enabling adaptation to the stringent...
10.
Porsch E, Yagupsky P, St Geme 3rd J
PLoS One
. 2020 Oct;
15(10):e0241511.
PMID: 33125432
Kingella negevensis is a newly described gram-negative bacterium in the Neisseriaceae family and is closely related to Kingella kingae, an important cause of pediatric osteoarticular infections and other invasive diseases....