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Erdong Liu

Explore the profile of Erdong Liu including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 859
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Recent Articles
1.
Chen J, Jiang Y, Hou M, Liu C, Liu E, Zong Y, et al.
Gut . 2024 Sep; 74(1):128-140. PMID: 39349007
Background: The potency of T cell-mediated responses is a determinant of immunotherapy effectiveness in treating malignancies; however, the clinical efficacy of T-cell therapies has been limited in hepatocellular carcinoma (HCC)...
2.
Li Y, Liu E, Gu H, Lou J, Yang Y, Ban L, et al.
Molecules . 2023 Jan; 28(1). PMID: 36615490
Energy is indispensable in human life and social development, but this has led to an overconsumption of non-renewable energy. Sustainable energy is needed to maintain the global energy balance. Lignocellulose...
3.
Cui X, Han L, Cui L, Fu G, Liu E, Wang D, et al.
Pharmacol Res . 2022 Dec; 187:106583. PMID: 36574578
The heterogeneity of tumor immune microenvironment (TIME) plays important roles in the development and immunotherapy response of hepatocellular carcinoma (HCC). Using machine learning algorithms, we introduced the immune index (IMI),...
4.
Jia D, Liu C, Zhu Z, Cao Y, Wen W, Hong Z, et al.
Clin Transl Med . 2022 Oct; 12(11):e1095. PMID: 36314067
Background: Transketolase (TKT), a key rate-limiting enzyme in the non-oxidative branch of the pentose phosphate pathway (PPP), provides more than 85% of the ribose required for de novo nucleotide biosynthesis...
5.
Wang X, Liu C, Chen J, Chen L, Ren X, Hou M, et al.
Cell Discov . 2022 Oct; 8(1):101. PMID: 36198671
Gallbladder carcinoma (GBC) is the most common biliary tract malignancy with the lowest survival rate, primarily arising from chronic inflammation. To better characterize the progression from inflammation to cancer to...
6.
Yuan B, Zhao X, Wang X, Liu E, Liu C, Zong Y, et al.
Clin Transl Med . 2022 Jan; 12(1):e678. PMID: 35075805
Background: Gallbladder carcinoma (GBC) is a relatively rare but highly aggressive cancer with late clinical detection and a poor prognosis. However, the lack of models with features consistent with human...
7.
Deng H, Zhai H, Shi Y, Liu G, Lowry J, Liu B, et al.
Commun Biol . 2021 Mar; 4(1):396. PMID: 33767386
CRISPR/Cas9-mediated genome editing provides potential for therapeutic development. Efficacy and long-term safety represent major concerns that remain to be adequately addressed in preclinical studies. Here we show that CRISPR/Cas9-mediated genome...
8.
Radzicki D, Liu E, Deng H, Siddique T, Martina M
Front Cell Neurosci . 2016 Oct; 10:216. PMID: 27703430
Frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) are believed to represent the different outcomes of a common pathogenic mechanism. However, while researchers have intensely studied the involvement of motor...
9.
Gorrie G, Fecto F, Radzicki D, Weiss C, Shi Y, Dong H, et al.
Proc Natl Acad Sci U S A . 2014 Sep; 111(40):14524-9. PMID: 25246588
Mutations in the gene encoding ubiquilin2 (UBQLN2) cause amyotrophic lateral sclerosis (ALS), frontotemporal type of dementia, or both. However, the molecular mechanisms are unknown. Here, we show that ALS/dementia-linked UBQLN2(P497H)...
10.
Fecto F, Yan J, Vemula S, Liu E, Yang Y, Chen W, et al.
Arch Neurol . 2011 Nov; 68(11):1440-6. PMID: 22084127
Background: The SQSTM1 gene encodes p62, a major pathologic protein involved in neurodegeneration. Objective: To examine whether SQSTM1 mutations contribute to familial and sporadic amyotrophic lateral sclerosis (ALS). Design: Case-control...