Enza Lacivita
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Explore the profile of Enza Lacivita including associated specialties, affiliations and a list of published articles.
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109
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1166
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Recent Articles
1.
Francavilla F, Intranuovo F, La Spada G, Lacivita E, Catto M, Graps E, et al.
ChemMedChem
. 2024 Dec;
:e202400672.
PMID: 39651728
Aging naturally involves a decline in biological functions, often triggering a disequilibrium of physiological processes. A common outcome is the altered response exerted by the immune system to counteract infections,...
2.
Alterations of synaptic plasticity in Angelman syndrome model mice are rescued by 5-HT7R stimulation
Pizzella A, Penna E, Liu Y, Abate N, Lacivita E, Leopoldo M, et al.
Prog Neurobiol
. 2024 Oct;
242:102684.
PMID: 39481590
Angelman syndrome (AS) is a severe neurodevelopmental disorder characterized by motor disfunction, seizures, intellectual disability, speech deficits, and autism-like behavior, showing high comorbidity with Autism Spectrum Disorders (ASD). It is...
3.
Ghafir El Idrissi I, Santo A, Lacivita E, Leopoldo M
Pharmaceuticals (Basel)
. 2024 Sep;
17(9).
PMID: 39338400
Serotonin (5-hydroxytryptamine, 5-HT) is a ubiquitous neurotransmitter in the human body. In the central nervous system, 5-HT affects sleep, pain, mood, appetite, and attention, while in the peripheral nervous system,...
4.
Brunetti L, Francavilla F, Leopoldo M, Lacivita E
Pharmaceuticals (Basel)
. 2024 Jun;
17(6).
PMID: 38931362
Serotonin (5-hydroxytryptamine, 5-HT) is a neurotransmitter regulating numerous physiological functions, and its dysregulation is a crucial component of the pathological processes of schizophrenia, depression, migraines, and obesity. 5-HT interacts with...
5.
Speranza L, Molinari M, Volpicelli F, Lacivita E, Leopoldo M, Pulcrano S, et al.
Brain Res
. 2024 Feb;
1830:148815.
PMID: 38387714
Antipsychotic drugs (APDs) are the primary pharmacological treatment for schizophrenia, a complex disorder characterized by altered neuronal connectivity. Atypical or second-generation antipsychotics, such as Risperidone (RSP) and Clozapine (CZP) predominantly...
6.
Tylek K, Trojan E, Leskiewicz M, Ghafir El Idrissi I, Lacivita E, Leopoldo M, et al.
Cells
. 2023 Nov;
12(21).
PMID: 37947648
Microglial cells have been demonstrated to be significant resident immune cells that maintain homeostasis under physiological conditions. However, prolonged or excessive microglial activation leads to disturbances in the resolution of...
7.
Francavilla F, Sarcina F, Schepetkin I, Kirpotina L, Contino M, Schirizzi A, et al.
Eur J Med Chem
. 2023 Oct;
261:115854.
PMID: 37839346
Formyl peptide receptor-1 (FPR1) is a G protein-coupled chemoattractant receptor that plays a crucial role in the trafficking of leukocytes into the sites of bacterial infection and inflammation. Recently, FPR1...
8.
Tylek K, Trojan E, Leskiewicz M, Francavilla F, Lacivita E, Leopoldo M, et al.
ACS Chem Neurosci
. 2023 Sep;
14(20):3869-3882.
PMID: 37775304
A substantial body of evidence demonstrates an association between a malfunction in the resolution of acute inflammation and the development of chronic inflammation. Recently, in this context, the importance of...
9.
Evaluating the effect of R-Baclofen and LP-211 on autistic behavior of the BTBR and -KO mouse models
Sharghi S, Flunkert S, Daurer M, Rabl R, Chagnaud B, Leopoldo M, et al.
Front Neurosci
. 2023 Apr;
17:1087788.
PMID: 37065917
Introduction: Autism spectrum disorder (ASD) is a persistent neurodevelopmental condition characterized by two core behavioral symptoms: impaired social communication and interaction, as well as stereotypic, repetitive behavior. No distinct cause...
10.
Ghafir El Idrissi I, Podlewska S, Abate C, Bojarski A, Lacivita E, Leopoldo M
Curr Med Chem
. 2023 Apr;
31(11):1361-1403.
PMID: 37013427
The purinergic P2X7 receptor (P2X7R), an ATP-gated non-selective cation channel, has emerged as a gatekeeper of inflammation that controls the release of proinflammatory cytokines. As a key player in initiating...