Eng-King Tan
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Explore the profile of Eng-King Tan including associated specialties, affiliations and a list of published articles.
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394
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6706
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Recent Articles
1.
Wang J, Chan C, Chua W, Chao Y, Chan L, Tan E
Eur J Neurol
. 2025 Mar;
32(3):e70047.
PMID: 40035126
Introduction: Parkinson's disease (PD) is a common neurodegenerative disorder affecting more than 10 million people worldwide. The actual prevalence and relative risk of venous thromboembolism (VTE) in PD have not...
2.
Chang C, Chew E, Lian M, Tandiono M, Li Z, Chung S, et al.
J Parkinsons Dis
. 2025 Feb;
:1877718X241300298.
PMID: 39973496
Genome-wide association studies have identified as a Parkinson's disease (PD) risk locus, with a common missense variant p.Asp543Asn in the synaptic vesicle glycoprotein 2C (SV2C) protein significantly associated with PD....
3.
Xiao B, Tan E
NPJ Parkinsons Dis
. 2025 Feb;
11(1):31.
PMID: 39971932
A post hoc subgroup analysis has suggested potential therapeutic benefits of prasinezumab, a humanized monoclonal anti-α-synuclein antibody, in patients with rapidly progressing Parkinson's disease (PD), despite initial trials showing limited...
4.
Santhanakrishnan A, Tan Y, Saffari S, Zhao Y, Ng E, Ng S, et al.
Aging (Albany NY)
. 2025 Feb;
17(2):357-364.
PMID: 39907500
Alpha-synuclein gene promoter (SNCA Rep1) polymorphism has been linked to Parkinson's Disease (PD) susceptibility and motor symptom severity, but less is known about its longitudinal relationship with non-motor symptom severity....
5.
Liu Y, Wang X, Wang X, Yin M, Tan M, Wang C, et al.
Parkinsonism Relat Disord
. 2025 Feb;
132:107306.
PMID: 39893775
Background: Acoustic prosodic analysis is a novel approach that can be used to identify patients with mild cognitive impairment (MCI) and dementia in Alzheimer's disease (AD). We hypothesize that acoustic...
6.
Chua W, Chan C, Wang J, Chan L, Tan E
Can J Neurol Sci
. 2025 Jan;
:1-12.
PMID: 39801211
Background: Parkinson disease (PD) is a neurological disorder that affects more than 10 million people worldwide, impacting both quality of life and marital relationships. Divorce rates are higher in Western...
7.
Mohammadi R, Ng S, Tan J, Ng A, Deng X, Choi X, et al.
Biomedicines
. 2025 Jan;
12(12.
PMID: 39767666
: Parkinson's disease (PD) is the second most common neurodegenerative disease, primarily affecting the middle-aged to elderly population. Among its nonmotor symptoms, cognitive decline (CD) is a precursor to dementia...
8.
Zhu S, Li H, Huang Z, Zeng Y, Huang J, Li G, et al.
NPJ Parkinsons Dis
. 2025 Jan;
11(1):1.
PMID: 39747089
In a prospective longitudinal study with 218 Parkinson's disease (PD) patients in the discovery cohort and 84 in the validation cohort, we aimed to identify novel blood biomarkers predicting disability...
9.
Tu H, Yeo X, Zhang Z, Zhou W, Tan J, Chi L, et al.
Mol Neurodegener
. 2024 Nov;
19(1):91.
PMID: 39609868
Background: The expansion of GGC repeats (typically exceeding 60 repeats) in the 5' untranslated region (UTR) of the NOTCH2NLC gene (N2C) is linked to N2C-related repeat expansion disorders (NREDs), such...
10.
Chew E, Liu Z, Li Z, Chung S, Lian M, Tandiono M, et al.
Nat Aging
. 2024 Nov;
5(2):205-218.
PMID: 39572736
Parkinson's disease (PD) is an incurable, progressive and common movement disorder that is increasing in incidence globally because of population aging. We hypothesized that the landscape of rare, protein-altering variants...