Emy J Chen
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Explore the profile of Emy J Chen including associated specialties, affiliations and a list of published articles.
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6
Citations
397
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Recent Articles
1.
Hershkovitz D, Chen E, Ensminger A, Dugan A, Conway K, Joyce A, et al.
mSphere
. 2024 Aug;
9(9):e0022224.
PMID: 39166849
Importance: grows in a membrane-bound compartment in macrophages during disease. Construction of the compartment requires a dedicated secretion system that translocates virulence proteins into host cells. One of these proteins,...
2.
Hershkovitz D, Chen E, Ensminger A, Dugan A, Conway K, Joyce A, et al.
bioRxiv
. 2024 Apr;
PMID: 38562771
grows within membrane-bound vacuoles in phylogenetically diverse hosts. Intracellular growth requires the function of the Icm/Dot type-IVb secretion system, which translocates more than 300 proteins into host cells. A screen...
3.
Heidtman M, Chen E, Moy M, Isberg R
Cell Microbiol
. 2008 Nov;
11(2):230-48.
PMID: 19016775
The bacterial pathogen Legionella pneumophila replicates in a specialized vacuole within host cells. Establishment of the replication vacuole depends on the Dot/Icm translocation system that delivers a large number of...
4.
Barnes C, Huang S, Kaipainen A, Sanoudou D, Chen E, Eichler G, et al.
Proc Natl Acad Sci U S A
. 2005 Dec;
102(52):19097-102.
PMID: 16365311
The origin of the pathogenic endothelial cells in common infantile hemangioma is unknown. We show here that the transcriptomes of human placenta and infantile hemangioma are sufficiently similar to suggest...
5.
Chang L, Garcia-Cardena G, Farnebo F, Fannon M, Chen E, Butterfield C, et al.
Proc Natl Acad Sci U S A
. 2004 Aug;
101(32):11658-63.
PMID: 15289610
Spatio-temporal studies on the growth of capillary blood vessels and capillary lymphatic vessels in tissue remodeling have suggested that lymphangiogenesis is angiogenesis-dependent. We revisited this concept by using fibroblast growth...
6.
Panigrahy D, Singer S, Shen L, Butterfield C, Freedman D, Chen E, et al.
J Clin Invest
. 2002 Oct;
110(7):923-32.
PMID: 12370270
Several drugs approved for a variety of indications have been shown to exhibit antiangiogenic effects. Our study focuses on the PPARgamma ligand rosiglitazone, a compound widely used in the treatment...