Emmanuel Contassot
Overview
Explore the profile of Emmanuel Contassot including associated specialties, affiliations and a list of published articles.
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Articles
57
Citations
1801
Followers
0
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Recent Articles
1.
Lalevee S, Surenaud M, Tariq M, Ingen-Housz-Oro S, Jean-Louis F, Barau C, et al.
J Invest Dermatol
. 2025 Feb;
PMID: 39986436
No abstract available.
2.
Constantin D, Nosi V, Kehrer N, Vacchini A, Chancellor A, Contassot E, et al.
Cancer Immunol Res
. 2024 Jul;
12(10):1452-1467.
PMID: 39028853
The MHC class I-related molecule MR1 is ubiquitously expressed, is highly conserved among mammals, and presents bacterial and endogenous antigens in tumor cells. These features indicate that tumor-specific T cells...
3.
Schmauch E, Severin Y, Xing X, Mangold A, Conrad C, Johannsen P, et al.
Sci Adv
. 2024 Jul;
10(27):eado2365.
PMID: 38959302
Pityriasis rubra pilaris (PRP) is a rare inflammatory skin disease with a poorly understood pathogenesis. Through a molecularly driven precision medicine approach and an extensive mechanistic pathway analysis in PRP...
4.
5.
Agarwal R, Dittmar T, Beer H, Kunz M, Muller S, Kappos E, et al.
Exp Dermatol
. 2023 Apr;
32(7):1143-1155.
PMID: 37114406
The translatability of research is highly dependent on models that recapitulate human tissues and organs. Here, we describe a procedure for the generation of human epidermis organotypic cultures (HEOCs) from...
6.
Spalinger M, Kasper S, Gottier C, Lang S, Atrott K, Vavricka S, et al.
J Clin Invest
. 2023 Feb;
133(4).
PMID: 36787260
No abstract available.
7.
Schmidt V, Lalevee S, Traidl S, Ameri M, Ziadlou R, Ingen-Housz-Oro S, et al.
Allergy
. 2022 Dec;
78(5):1280-1291.
PMID: 36463488
Background: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare but potentially life-threatening cutaneous adverse reactions. There is still no consensus on adjuvant treatments, and little is known about...
8.
Meier-Schiesser B, Mellett M, Ramirez-Fort M, Maul J, Klug A, Winkelbeiner N, et al.
Int J Mol Sci
. 2021 Dec;
22(23).
PMID: 34884681
Apremilast (Otezla) is an oral small molecule phosphodiesterase 4 (PDE4) inhibitor approved for the treatment of psoriasis, psoriatic arthritis, and oral ulcers associated with Behçet's disease. While PDE4 inhibition overall...
9.
Contassot E, French L
J Invest Dermatol
. 2021 Feb;
141(3):476-478.
PMID: 33618803
Verma et al. (2021) demonstrate that TNF antagonists unexpectedly downregulate systemic IL-1β by inhibiting noncanonical inflammasome activation in patients with psoriasis. Given the known involvement of IL-1β in the pathogenesis...
10.
Satoh T, Mellett M, Meier-Schiesser B, Fenini G, Otsuka A, Beer H, et al.
J Clin Invest
. 2019 Dec;
130(3):1417-1430.
PMID: 31805013
Epidermal growth factor receptor (EGFR) and MEK inhibitors (EGFRi/MEKi) are beneficial for the treatment of solid cancers but are frequently associated with severe therapy-limiting acneiform skin toxicities. The underlying molecular...