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Emma L Dolan

Explore the profile of Emma L Dolan including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 158
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Recent Articles
1.
King D, Beard E, Satusky M, Ryde I, George A, Johnson C, et al.
bioRxiv . 2024 Nov; PMID: 39484377
Mitochondria lack nucleotide excision DNA repair; however, mitochondrial DNA (mtDNA) is resistant to mutation accumulation following DNA damage. These observations suggest additional damage sensing or protection mechanisms. Transcription Factor A,...
2.
Safi R, Wardell S, Watkinson P, Qin X, Lee M, Park S, et al.
Nat Commun . 2024 Sep; 15(1):7675. PMID: 39227594
Most prostate cancers express the androgen receptor (AR), and tumor growth and progression are facilitated by exceptionally low levels of systemic or intratumorally produced androgens. Thus, absolute inhibition of the...
3.
King D, Lalwani P, Mercado G, Dolan E, Frierson J, Meyer J, et al.
Front Genet . 2024 Feb; 15:1348855. PMID: 38356697
The field of environmental epigenetics is uniquely suited to investigate biologic mechanisms that have the potential to link stressors to health disparities. However, it is common practice in basic epigenetic...
4.
Wu A, Gossa S, Samala R, Chung M, Gril B, Yang H, et al.
Clin Cancer Res . 2021 Jun; 27(15):4422-4434. PMID: 34083229
Purpose: Breast cancer diagnosed in young patients is often aggressive. Because primary breast tumors from young and older patients have similar mutational patterns, we hypothesized that the young host microenvironment...
5.
Gril B, Paranjape A, Woditschka S, Hua E, Dolan E, Hanson J, et al.
Nat Commun . 2018 Jul; 9(1):2705. PMID: 30006619
Brain metastases are devastating complications of cancer. The blood-brain barrier (BBB), which protects the normal brain, morphs into an inadequately characterized blood-tumor barrier (BTB) when brain metastases form, and is...
6.
Mohammad A, Griffith J, Adkins C, Shah N, Sechrest E, Dolan E, et al.
Pharm Res . 2018 Jan; 35(2):31. PMID: 29368289
Purpose: The blood-tumor barrier (BTB) limits irinotecan distribution in tumors of the central nervous system. However, given that the BTB has increased passive permeability we hypothesize that liposomal irinotecan would...
7.
Bohn K, Adkins C, Mittapalli R, Terrell-Hall T, Mohammad A, Shah N, et al.
J Neurosci Methods . 2016 Jun; 270:124-131. PMID: 27321229
Background: Measurement of vascular density has significant value in characterizing healthy and diseased tissue, particularly in brain where vascular density varies among regions. Further, an understanding of brain vessel size...
8.
Adkins C, Mohammad A, Terrell-Hall T, Dolan E, Shah N, Sechrest E, et al.
Clin Exp Metastasis . 2016 Mar; 33(4):373-83. PMID: 26944053
The blood-brain barrier (BBB) is compromised in brain metastases, allowing for enhanced drug permeation into brain. The extent and heterogeneity of BBB permeability in metastatic lesions is important when considering...