Emilie Lameignere
Overview
Explore the profile of Emilie Lameignere including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
410
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Recent Articles
1.
Pang S, Wijeyewickrema L, Hor L, Tan S, Lameignere E, Conway E, et al.
J Immunol
. 2017 Oct;
199(11):3883-3891.
PMID: 29061764
Complement is crucial to the immune response, but dysregulation of the system causes inflammatory disease. Complement is activated by three pathways: classical, lectin, and alternative. The classical and lectin pathways...
2.
Wijeyewickrema L, Lameignere E, Hor L, Duncan R, Shiba T, Travers R, et al.
Blood
. 2016 Jun;
128(13):1766-76.
PMID: 27338096
The complement system plays a key role in innate immunity, inflammation, and coagulation. The system is delicately balanced by negative regulatory mechanisms that modulate the host response to pathogen invasion...
3.
Volkers G, Worrall L, Kwan D, Yu C, Baumann L, Lameignere E, et al.
Nat Struct Mol Biol
. 2015 Jul;
22(8):627-35.
PMID: 26192331
Sialyltransferases of the mammalian ST8Sia family catalyze oligo- and polysialylation of surface-localized glycoproteins and glycolipids through transfer of sialic acids from CMP-sialic acid to the nonreducing ends of sialic acid...
4.
Solomonson M, Setiaputra D, Makepeace K, Lameignere E, Petrotchenko E, Conrady D, et al.
Structure
. 2015 Feb;
23(3):571-583.
PMID: 25684576
Mycobacterium tuberculosis (Mtb) uses the ESX-1 type VII secretion system to export virulence proteins across its lipid-rich cell wall, which helps permeabilize the host's macrophage phagosomal membrane, facilitating the escape...
5.
Burkinshaw B, Deng W, Lameignere E, Wasney G, Zhu H, Worrall L, et al.
J Biol Chem
. 2015 Feb;
290(16):10406-17.
PMID: 25678709
The Gram-negative bacterium enteropathogenic Escherichia coli uses a syringe-like type III secretion system (T3SS) to inject virulence or "effector" proteins into the cytoplasm of host intestinal epithelial cells. To assemble,...
6.
Sobhanifar S, Worrall L, Gruninger R, Wasney G, Blaukopf M, Baumann L, et al.
Proc Natl Acad Sci U S A
. 2015 Jan;
112(6):E576-85.
PMID: 25624472
Unique to Gram-positive bacteria, wall teichoic acids are anionic glycopolymers cross-stitched to a thick layer of peptidoglycan. The polyol phosphate subunits of these glycopolymers are decorated with GlcNAc sugars that...
7.
Bergeron J, Worrall L, De S, Sgourakis N, Cheung A, Lameignere E, et al.
Structure
. 2014 Dec;
23(1):161-172.
PMID: 25533490
The type III secretion system (T3SS) is a large macromolecular assembly found at the surface of many pathogenic Gram-negative bacteria. Its role is to inject toxic "effector" proteins into the...
8.
King D, Lameignere E, Strynadka N
J Biol Chem
. 2014 May;
289(27):19245-53.
PMID: 24808177
In bacteria, the synthesis of the protective peptidoglycan sacculus is a dynamic process that is tightly regulated at multiple levels. Recently, the lipoprotein co-factor LpoB has been found essential for...
9.
Wat J, Foley J, Krisinger M, Ocariza L, Lei V, Wasney G, et al.
Blood
. 2013 Dec;
123(5):768-76.
PMID: 24335501
Polyphosphate, synthesized by all cells, is a linear polymer of inorganic phosphate. When released into the circulation, it exerts prothrombotic and proinflammatory activities by modulating steps in the coagulation cascade....
10.
Marchetti R, Malinovska L, Lameignere E, Adamova L, De Castro C, Cioci G, et al.
Glycobiology
. 2012 Jul;
22(10):1387-98.
PMID: 22763039
Bacteria from the Burkholderia cepacia complex (Bcc) cause highly contagious pneumonia among cystic fibrosis (CF) patients. Among them, Burkholderia cenocepacia is one of the most dangerous in the Bcc and...