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Emiko Urano

Explore the profile of Emiko Urano including associated specialties, affiliations and a list of published articles. Areas
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Articles 39
Citations 368
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Recent Articles
1.
Urano E, Itoh Y, Suzuki T, Sasaki T, Kishikawa J, Akamatsu K, et al.
Sci Transl Med . 2023 Aug; 15(711):eadi2623. PMID: 37647387
The Omicron variant continuously evolves under the humoral immune pressure exerted by vaccination and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, and the resulting Omicron subvariants display further immune...
2.
Shofa M, Okamura T, Urano E, Matsuura Y, Yasutomi Y, Saito A
Int J Mol Sci . 2022 Nov; 23(22). PMID: 36430481
Zika virus (ZIKV) outbreaks in Central and South America caused severe public health problems in 2015 and 2016. These outbreaks were finally contained through several methods, including mosquito control using...
3.
Urano E, Ueda K, Higuchi M, Furukawa M, Okamura T, Tanaka Y, et al.
J Virol . 2022 Oct; 96(22):e0133922. PMID: 36314828
Human T-cell leukemia virus type 1 (HTLV-1) is the causative agent of adult T-cell leukemia (ATL) and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). However, the precise mechanisms leading to HTLV-1 chronic...
4.
Nagatake T, Kishino S, Urano E, Murakami H, Kitamura N, Konishi K, et al.
Mucosal Immunol . 2022 Jan; 15(2):289-300. PMID: 35013573
Dietary ω3 fatty acids have important health benefits and exert their potent bioactivity through conversion to lipid mediators. Here, we demonstrate that microbiota play an essential role in the body's...
5.
Urano E, Okamura T, Ono C, Ueno S, Nagata S, Kamada H, et al.
Proc Natl Acad Sci U S A . 2021 Oct; 118(43). PMID: 34625475
The pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a global threat to human health and life. A useful pathological animal model accurately reflecting human pathology is needed...
6.
Tsujimura Y, Shiogama Y, Soma S, Okamura T, Takano J, Urano E, et al.
J Immunol . 2020 Oct; 205(11):3023-3036. PMID: 33097574
Recently, the efficacy of bacillus Calmette-Guérin (BCG) vaccination is being reassessed in accordance with the achievements of clinical tuberculosis (TB) vaccine research. However, the mechanisms ultimately determining the success or...
7.
Urano E, Timilsina U, Kaplan J, Ablan S, Ghimire D, Pham P, et al.
J Virol . 2018 Dec; 93(6). PMID: 30567982
A betulinic acid-based compound, bevirimat (BVM), inhibits HIV-1 maturation by blocking a late step in protease-mediated Gag processing: the cleavage of the capsid-spacer peptide 1 (CA-SP1) intermediate to mature CA....
8.
Wang M, Quinn C, Perilla J, Zhang H, Shirra Jr R, Hou G, et al.
Nat Commun . 2017 Nov; 8(1):1779. PMID: 29176596
Maturation of HIV-1 particles encompasses a complex morphological transformation of Gag via an orchestrated series of proteolytic cleavage events. A longstanding question concerns the structure of the C-terminal region of...
9.
Urano E, Miyauchi K, Kojima Y, Hamatake M, Ablan S, Fudo S, et al.
ChemMedChem . 2016 Sep; 11(20):2320-2326. PMID: 27634404
A novel HIV-1 inhibitor, 6-(tert-butyl)-4-phenyl-4-(trifluoromethyl)-1H,3H-1,3,5-triazin-2-one (compound 1), was identified from a compound library screened for the ability to inhibit HIV-1 replication. EC values of compound 1 were found to range...
10.
Takeda S, Takizawa M, Miyauchi K, Urano E, Fujino M, Murakami T, et al.
Biochem Biophys Res Commun . 2016 May; 475(1):113-8. PMID: 27178216
The conformational dynamics of the HIV-1 envelope glycoprotein gp120 and gp41 (Env) remains poorly understood. Here we examined how the V3 loop conformation is regulated in the liganded state using...