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Eman M Meky

Explore the profile of Eman M Meky including associated specialties, affiliations and a list of published articles. Areas
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Articles 3
Citations 136
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Recent Articles
1.
Rajderkar S, Barozzi I, Zhu Y, Hu R, Zhang Y, Li B, et al.
Commun Biol . 2023 Apr; 6(1):435. PMID: 37081156
Topologically associating domain (TAD) boundaries partition the genome into distinct regulatory territories. Anecdotal evidence suggests that their disruption may interfere with normal gene expression and cause disease phenotypes, but the...
2.
Osterwalder M, Tran S, Hunter R, Meky E, von Maydell K, Harrington A, et al.
Methods Mol Biol . 2021 Dec; 2403:147-186. PMID: 34913122
Embryonic morphogenesis is strictly dependent on tight spatiotemporal control of developmental gene expression, which is typically achieved through the concerted activity of multiple enhancers driving cell type-specific expression of a...
3.
Kvon E, Zhu Y, Kelman G, Novak C, Plajzer-Frick I, Kato M, et al.
Cell . 2020 Mar; 180(6):1262-1271.e15. PMID: 32169219
Establishing causal links between non-coding variants and human phenotypes is an increasing challenge. Here, we introduce a high-throughput mouse reporter assay for assessing the pathogenic potential of human enhancer variants...