Else K Hoffmann
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Explore the profile of Else K Hoffmann including associated specialties, affiliations and a list of published articles.
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37
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1602
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Recent Articles
1.
Kirkegaard S, Strom P, Gammeltoft S, Hansen A, Hoffmann E
Cell Physiol Biochem
. 2016 Feb;
38(3):883-92.
PMID: 26909737
Background/aims: The potential role of the two-pore domain potassium channel KCNK5 (also known as TASK-2 and K(2P)5.1) in activated T cell physiology has only recently been described. So far KCNK5...
2.
Hoffmann E, Sorensen B, Sauter D, Lambert I
Channels (Austin)
. 2015 Nov;
9(6):380-96.
PMID: 26569161
Volume-regulated channels for anions (VRAC) / organic osmolytes (VSOAC) play essential roles in cell volume regulation and other cellular functions, e.g. proliferation, cell migration and apoptosis. LRRC8A, which belongs to...
3.
Hoffmann E, Lambert I
Philos Trans R Soc Lond B Biol Sci
. 2014 Feb;
369(1638):20130109.
PMID: 24493757
Multi-drug resistance (MDR) to chemotherapy is the major challenge in the treatment of cancer. MDR can develop by numerous mechanisms including decreased drug uptake, increased drug efflux and the failure...
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Pedersen S, Hoffmann E, Novak I
Front Physiol
. 2013 Sep;
4:233.
PMID: 24009588
The physiological function of epithelia is transport of ions, nutrients, and fluid either in secretory or absorptive direction. All of these processes are closely related to cell volume changes, which...
7.
Lang F, Hoffmann E
Compr Physiol
. 2013 Jun;
2(3):2037-61.
PMID: 23723032
Cell shrinkage is a hallmark and contributes to signaling of apoptosis. Apoptotic cell shrinkage requires ion transport across the cell membrane involving K(+) channels, Cl(-) or anion channels, Na(+)/H(+) exchange,...
8.
Grubb S, Poulsen K, Juul C, Kyed T, Klausen T, Larsen E, et al.
J Gen Physiol
. 2013 May;
141(5):585-600.
PMID: 23630341
Members of the TMEM16 (Anoctamin) family of membrane proteins have been shown to be essential constituents of the Ca(2+)-activated Cl(-) channel (CaCC) in many cell types. In this study, we...
9.
Jorgensen S, Eriksen H, Dausell J, Jespersen T, Lambert I, Hoffmann E
Cell Physiol Biochem
. 2013 Mar;
31(2-3):366-78.
PMID: 23485744
Background/aims: Signalling via CysLT1 is involved in activation of volume sensitive K(+) channels and homologous desensitization of the LTD4 receptor impairs regulatory volume decrease (RVD). The aim is to illustrate...
10.
Eduardsen K, Larsen S, Novak I, Lambert I, Hoffmann E, Pedersen S
Cell Physiol Biochem
. 2011 Dec;
28(6):1231-46.
PMID: 22179011
Caveolae have been implicated in sensing of cell volume perturbations, yet evidence is still limited and findings contradictory. Here, we investigated the possible role of caveolae in cell volume regulation...