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Ellyn Shocron

Explore the profile of Ellyn Shocron including associated specialties, affiliations and a list of published articles. Areas
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Articles 3
Citations 29
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Recent Articles
1.
Tang C, Parham C, Shocron E, McMahon G, Patel N
Cancer Chemother Pharmacol . 2010 Sep; 67(6):1389-400. PMID: 20809122
Purpose: Picoplatin is a new generation platinum designed to overcome platinum resistance. The goal of this study was to assess picoplatin anti-tumor activity and measure various cellular parameters in small-cell...
2.
Li X, Shocron E, Song A, Patel N, Sun C
Bioorg Med Chem Lett . 2009 Apr; 19(10):2860-4. PMID: 19395259
A new series of compounds, 5-substituted 2-amino-4-chloro-8-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-7,8-dihydropteridin-6(5H)-ones, have been designed and identified as potent and selective inhibitors of Hsp90. These compounds demonstrated nanomolar potency toward both Hsp90-regulated Her2 degradation and...
3.
Oskouian B, Mendel J, Shocron E, Lee Jr M, Fyrst H, Saba J
J Biol Chem . 2005 Mar; 280(18):18403-10. PMID: 15734735
Sphingosine-1-phosphate is a bioactive sphingolipid that regulates proliferation, differentiation, migration, and apoptosis. Sphingosine-1-phosphate is irreversibly degraded by the highly conserved enzyme sphingosine-1-phosphate lyase. Recent studies have suggested that sphingosine-1-phosphate lyase...