Ellen J Beswick
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Explore the profile of Ellen J Beswick including associated specialties, affiliations and a list of published articles.
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63
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2496
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Recent Articles
1.
Tang W, Battistone B, Bauer K, Weis A, Barba C, Fadlullah M, et al.
Cell Rep
. 2025 Feb;
44(2):115301.
PMID: 39951377
The rising incidence of advanced-stage colorectal cancer (CRC) and poor survival outcomes necessitate new and effective therapies. Immune checkpoint inhibitors (ICIs), specifically anti-PD-1 therapy, show promise, yet clinical determinants of...
2.
Howe C, Chulkina M, Syrcle R, McAninch C, McAninch S, Pinchuk I, et al.
Inflamm Bowel Dis
. 2025 Feb;
PMID: 39937137
Background: CD4+ T cells contribute to chronic inflammation and fibrosis in inflammatory bowel disease (IBD), but the cellular mechanisms remain elusive. We have found that the mitogen-activated protein kinase 2...
3.
Cheng O, Lebish E, Jensen O, Jacenik D, Trivedi S, Cacioppo J, et al.
Scand J Immunol
. 2024 May;
100(3):e13391.
PMID: 38773691
Mucosal-associated invariant T (MAIT) cells are innate-like T cells that can be activated by microbial antigens and cytokines and are abundant in mucosal tissues including the colon. MAIT cells have...
4.
Lujan D, Ochoa J, Beswick E, Howard T, Hathaway H, Perrone-Bizzozero N, et al.
Biomedicines
. 2024 Feb;
12(2).
PMID: 38397942
RNA binding proteins (RBPs) post-transcriptionally regulate gene expression by associating with regulatory sequences in the untranslated regions of mRNAs. Cold-inducible RBP (CIRP) is a stress-induced RBP that was recently shown...
5.
Cheng O, Lebish E, Jensen O, Jacenik D, Trivedi S, Cacioppo J, et al.
bioRxiv
. 2024 Jan;
PMID: 38293128
Mucosal-associated invariant T (MAIT) cells are innate-like T cells that can be activated by microbial antigens and cytokines and are abundant in mucosal tissues including the colon. MAIT cells have...
6.
Chulkina M, Rohmer C, McAninch S, Panganiban R, Villeger R, Portolese A, et al.
J Crohns Colitis
. 2024 Jan;
18(7):1147-1161.
PMID: 38224550
Background: Mesenchymal stromal cells are suggested to play a critical role in Crohn's disease [CD]-associated fibrosis. MAPKAPK2 [MK2] has emerged as a potential therapeutic target to reduce inflammation in CD....
7.
Jacenik D, Lebish E, Beswick E
Front Immunol
. 2023 Jul;
14:1212100.
PMID: 37415974
Background: Immune cell composition is a critical and dynamic component of the tumor microenvironment, which has an impact on immunosuppression and progression of cancer. T cells, especially CD8 T cells,...
8.
Albtoush N, Queisser K, Zawerton A, Lauer M, Beswick E, Petrey A
Matrix Biol
. 2023 Jun;
121:149-166.
PMID: 37391162
In response to tissue injury, changes in the extracellular matrix (ECM) can directly affect the inflammatory response and contribute to disease progression or resolution. During inflammation, the glycosaminoglycan hyaluronan (HA)...
9.
Jacenik D, Hikisz P, Beswick E, Fichna J
Biochim Biophys Acta Mol Basis Dis
. 2023 Mar;
1869(5):166683.
PMID: 36878303
Among the numerous adhesion G protein-coupled receptors (GPCRs), adhesion G protein-coupled estrogen receptor F5 (ADGRF5) contains unique domains in the long N-terminal tail which can determine cell-cell and cell-matrix interaction...
10.
Lebish E, Morgan N, Valentine J, Beswick E
Pharmaceuticals (Basel)
. 2022 Dec;
15(12).
PMID: 36558958
Crohn's Disease (CD) and Ulcerative Colitis (UC) are the two major forms of inflammatory bowel disease (IBD), which are incurable chronic immune-mediated diseases of the gastrointestinal tract. Both diseases present...