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Ellen J Beswick

Explore the profile of Ellen J Beswick including associated specialties, affiliations and a list of published articles. Areas
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Articles 63
Citations 2496
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Recent Articles
11.
Villeger R, Chulkina M, Mifflin R, Markov N, Trieu J, Sinha M, et al.
Br J Cancer . 2022 Dec; 128(4):537-548. PMID: 36482184
Background: Increases in IL-6 by cancer-associated fibroblasts (CAFs) contribute to colon cancer progression, but the mechanisms involved in the increase of this tumor-promoting cytokine are unknown. The aim of this...
12.
Jacenik D, Karagiannidis I, Beswick E
Br J Cancer . 2022 Nov; 128(2):387-397. PMID: 36376448
Background: Immunotherapy of gastrointestinal cancers is challenging; however, several lines of evidence suggest that adoptive transfer of stimulated or modified immune cells support not only protective role of immune cells...
13.
Jacenik D, Lebish E, Beswick E
Int J Mol Sci . 2022 Nov; 23(21). PMID: 36362348
Cases of pancreatic neuroendocrine tumors (PNETs) are growing in number, and new treatment options are needed in order to improve patient outcomes. The mitogen-activated protein kinase-activated protein kinase 2 (MK2)...
14.
Egal E, Jacenik D, Soares H, Beswick E
Biochim Biophys Acta Rev Cancer . 2021 Oct; 1876(2):188640. PMID: 34695532
Pancreatic neuroendocrine tumors are rare types of pancreatic cancer formed from islet cells of pancreas. Clinical presentation of pancreatic neuroendocrine tumors depends on both tumor progression and hormone secretion status,...
15.
Zhang W, Karagiannidis I, Van Vliet E, Yao R, Beswick E, Zhou A
Analyst . 2021 Sep; 146(20):6124-6131. PMID: 34543367
Granulocyte colony-stimulating factor (G-CSF) is produced at high levels in several cancers and is directly linked with metastasis in gastrointestinal (GI) cancers. In order to further understand the alteration of...
16.
Queisser K, Mellema R, Middleton E, Portier I, Manne B, Denorme F, et al.
JCI Insight . 2021 Jul; 6(17). PMID: 34314391
Vascular injury has emerged as a complication contributing to morbidity in coronavirus disease 2019 (COVID-19). The glycosaminoglycan hyaluronan (HA) is a major component of the glycocalyx, a protective layer of...
17.
Karagiannidis I, Salataj E, Egal E, Beswick E
Cytokine . 2021 Mar; 142:155479. PMID: 33677228
Granulocyte colony-stimulating factor (G-CSF) is a cytokine most well-known for maturation and mobilization of bone marrow neutrophils. Although it is used therapeutically to treat chemotherapy induced neutropenia, it is also...
18.
Grim C, Noble R, Uribe G, Khanipov K, Johnson P, Koltun W, et al.
J Crohns Colitis . 2021 Jan; 15(8):1362-1375. PMID: 33506258
Background And Aims: Little is known about the presence and function of tissue-resident mesenchymal stem cells [MtSCs] within the gastrointestinal mucosa in health and inflammatory bowel disease [IBD]. The contribution...
19.
Chulkina M, Beswick E, Pinchuk I
Int J Mol Sci . 2020 Dec; 21(23). PMID: 33271941
The gastrointestinal (GI) mucosa is among the most complex systems in the body. It has a diverse commensal microbiome challenged continuously by food and microbial components while delivering essential nutrients...
20.
Karagiannidis I, Jerman S, Jacenik D, Phinney B, Yao R, Prossnitz E, et al.
Front Immunol . 2020 Oct; 11:1885. PMID: 33042110
Cytokines are known to shape the tumor microenvironment and although progress has been made in understanding their role in carcinogenesis, much remains to learn regarding their role in tumor growth...