Ellen Gravallese
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Explore the profile of Ellen Gravallese including associated specialties, affiliations and a list of published articles.
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9
Citations
717
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Recent Articles
1.
Chaugule S, Constantinou C, John A, Micha D, Eekhoff M, Gravallese E, et al.
Hum Gene Ther
. 2025 Feb;
36(5-6):597-617.
PMID: 39932815
Osteogenesis imperfecta (OI) is a rare genetic disorder characterized by bone fragility due to reduced bone quality, often accompanied by low bone mass, recurrent fractures, hearing loss, skeletal abnormalities, and...
2.
Tedeschi S, Hayashi K, Rosenthal A, Gill M, Marrugo J, Fukui S, et al.
Arthritis Rheumatol
. 2024 Jan;
76(6):936-941.
PMID: 38221723
Objective: Calcium pyrophosphate deposition (CPPD) disease was associated with osteopenia in two cross-sectional studies. We compared fracture risks in patients with acute calcium pyrophosphate (CPP) crystal arthritis versus matched comparators....
3.
Weisenfeld D, Zhang F, Donlin L, Jonsson A, Apruzzese W, Campbell D, et al.
Arthritis Rheumatol
. 2023 Oct;
76(3):356-362.
PMID: 37791989
Objective: Recent studies have uncovered diverse cell types and states in the rheumatoid arthritis (RA) synovium; however, limited data exist correlating these findings with patient-level clinical information. Using the largest...
4.
Bai Z, Bartelo N, Aslam M, Hale C, Blachere N, Parveen S, et al.
medRxiv
. 2023 Sep;
PMID: 37662384
One Sentence Summary: Machine Learning reveals synovial fibroblast genes related to pain affect sensory nerve growth in Rheumatoid Arthritis addresses unmet clinical need.
5.
Mikuls T, Fraenkel L, Gravallese E, Johnson S, Turner A, Saag K
Arthritis Rheumatol
. 2020 Nov;
73(3):548-549.
PMID: 33142024
No abstract available.
6.
Yang Y, Xie J, Chaugule S, Wang D, Kim J, Kim J, et al.
Mol Ther Methods Clin Dev
. 2020 May;
17:922-935.
PMID: 32405514
Improper activity of bone-resorbing osteoclasts results in low bone density and deterioration of bone structure, which increase the risk of fractures. Anti-resorptive therapies targeting osteoclasts have proven effective in preserving...
7.
Yang Y, Xie J, Wang D, Kim J, Tai P, Gravallese E, et al.
Nat Commun
. 2019 Jul;
10(1):2958.
PMID: 31273195
RNAi-based bone anabolic gene therapy has demonstrated initial success, but many practical challenges are still unmet. Here, we demonstrate that a recombinant adeno-associated virus 9 (rAAV9) is highly effective for...
8.
Orange D, Agius P, DiCarlo E, Robine N, Geiger H, Szymonifka J, et al.
Arthritis Rheumatol
. 2018 Feb;
70(5):690-701.
PMID: 29468833
Objective: In this study, we sought to refine histologic scoring of rheumatoid arthritis (RA) synovial tissue by training with gene expression data and machine learning. Methods: Twenty histologic features were...
9.
Schett G, Gravallese E
Nat Rev Rheumatol
. 2012 Sep;
8(11):656-64.
PMID: 23007741
Bone erosion is a central feature of rheumatoid arthritis and is associated with disease severity and poor functional outcome. Erosion of periarticular cortical bone, the typical feature observed on plain...
10.
Ji H, Pettit A, Ohmura K, Ortiz-Lopez A, Duchatelle V, Degott C, et al.
J Exp Med
. 2002 Jul;
196(1):77-85.
PMID: 12093872
In spontaneous inflammatory arthritis of K/BxN T cell receptor transgenic mice, the effector phase of the disease is provoked by binding of immunoglobulins (Igs) to joint surfaces. Inflammatory cytokines are...