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Ella Bhagyaraj

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Citations 282
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Recent Articles
1.
Kumar S, Arora R, Gupta S, Ahuja N, Bhagyaraj E, Nanduri R, et al.
Blood Adv . 2024 May; 8(14):3705-3717. PMID: 38748870
The regulation of red blood cell (RBC) homeostasis by erythropoietin (EPO) is critical for O2 transport and maintaining the adequate number of RBCs in vertebrates. Therefore, dysregulation in EPO synthesis...
2.
Ahuja N, Gupta S, Arora R, Bhagyaraj E, Tiwari D, Kumar S, et al.
Life Sci Alliance . 2024 Apr; 7(7). PMID: 38609183
Elevated ER stress has been linked to the pathogenesis of several disease conditions including neurodegeneration. In this study, we have holistically determined the differential expression of all the nuclear receptors...
3.
Yang X, Goodwin Z, Bhagyaraj E, Hoffman C, Pascual D
Microorganisms . 2024 Jan; 12(1). PMID: 38257995
Susceptibility to brucellosis remains prevalent, even in herds vaccinated with conventional vaccines. Efforts are underway to develop an improved brucellosis vaccine, and possibly a universal vaccine, given that species are...
4.
Pascual D, Goodwin Z, Bhagyaraj E, Hoffman C, Yang X
Front Microbiol . 2023 Jan; 13:1018165. PMID: 36620020
Brucellosis is a disease of livestock that is commonly asymptomatic until an abortion occurs. Disease in humans results from contact of infected livestock or consumption of contaminated milk or meat....
5.
Tiwari D, Ahuja N, Kumar S, Kalra R, Nanduri R, Gupta S, et al.
Cell Mol Life Sci . 2022 May; 79(6):308. PMID: 35596832
Nuclear receptors are a unique family of transcription factors that play cardinal roles in physiology and plethora of human diseases. The adopted orphan nuclear receptor Nr1d1 is a constitutive transcriptional...
6.
Kalra R, Tiwari D, Dkhar H, Bhagyaraj E, Kumar R, Bhardwaj A, et al.
Int Rev Immunol . 2021 Oct; 42(1):43-70. PMID: 34678117
Introduction: Despite new approaches in the diagnosis and treatment of tuberculosis (TB), it continues to be a major health burden. Several immunotherapies that potentiate the immune response have come up...
7.
Nelson A, Akgul A, Maddaloni M, Bhagyaraj E, Hoffman C, Pascual D
Immunol Lett . 2021 Aug; 239:12-19. PMID: 34333043
Colonization factor antigen I (CFA/I) fimbria, an adhesin from enterotoxigenic Escherichia coli, confers protection in murine autoimmune models for type 1 diabetes (T1D), multiple sclerosis, and rheumatoid arthritis. Although CFA/I...
8.
Bhagyaraj E, Wang H, Yang X, Hoffman C, Akgul A, Goodwin Z, et al.
Front Immunol . 2021 Jul; 12:697953. PMID: 34305935
Past studies with the live, double-mutant  (znBAZ) strain resulted in nearly complete protection of mice against pulmonary challenge with wild-type (wt) a dominant CD8 T cell response. To understand the...
9.
Akgul A, Maddaloni M, Jun S, Nelson A, Odreman V, Hoffman C, et al.
Arthritis Res Ther . 2021 Apr; 23(1):99. PMID: 33823920
Background: Sjögren's syndrome (SjS), one of the most common autoimmune diseases, impacts millions of people annually. SjS results from autoimmune attack on exocrine (salivary and lacrimal) glands, and women are...
10.
Kumar S, Nanduri R, Bhagyaraj E, Kalra R, Ahuja N, Chacko A, et al.
Autophagy . 2020 Sep; 17(9):2273-2289. PMID: 32917126
Macrophage derived foam cells in atherosclerotic plaques are the major factor responsible for the pathogenesis of atherosclerosis (AS). During advanced AS, macrophage-specific macroautophagy/autophagy is dysfunctional. 1, 25-dihydroxy vitamin D3 (VitD3)...