Elke A Ober
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Explore the profile of Elke A Ober including associated specialties, affiliations and a list of published articles.
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36
Citations
1685
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Recent Articles
1.
Ambrosio E, Bailey C, Unterweger I, Christensen J, Bruchez M, Lundegaard P, et al.
Development
. 2024 Feb;
151(4).
PMID: 38381702
The liver restores its mass and architecture after injury. Yet, investigating morphogenetic cell behaviours and signals that repair tissue architecture at high spatiotemporal resolution remains challenging. We developed LiverZap, a...
2.
Unterweger I, Klepstad J, Hannezo E, Lundegaard P, Trusina A, Ober E
PLoS Biol
. 2023 Oct;
21(10):e3002315.
PMID: 37792696
To meet the physiological demands of the body, organs need to establish a functional tissue architecture and adequate size as the embryo develops to adulthood. In the liver, uni- and...
3.
Morgan K, Doggett K, Geng F, Mieruszynski S, Whitehead L, Smith K, et al.
Elife
. 2023 Jan;
12.
PMID: 36648336
The nucleoporin (NUP) ELYS, encoded by , is a large multifunctional protein with essential roles in nuclear pore assembly and mitosis. Using both larval and adult zebrafish models of hepatocellular...
4.
Caviglia S, Unterweger I, Gasiunaite A, Vanoosthuyse A, Cutrale F, Trinh L, et al.
Development
. 2022 Aug;
149(16).
PMID: 35980363
Visualizing cell shapes and interactions of differentiating cells is instrumental for understanding organ development and repair. Across species, strategies for stochastic multicolour labelling have greatly facilitated in vivo cell tracking...
5.
Dzementsei A, Barooji Y, Ober E, Oddershede L
Commun Biol
. 2022 Apr;
5(1):402.
PMID: 35488088
Material properties of living matter play an important role for biological function and development. Yet, quantification of material properties of internal organs in vivo, without causing physiological damage, remains challenging....
6.
Thestrup M, Caviglia S, Cayuso J, Heyne R, Ahmad R, Hofmeister W, et al.
Nat Commun
. 2019 Nov;
10(1):5220.
PMID: 31745086
The hepatopancreatic ductal (HPD) system connects the intrahepatic and intrapancreatic ducts to the intestine and ensures the afferent transport of the bile and pancreatic enzymes. Yet the molecular and cellular...
7.
Caviglia S, Ober E
Curr Opin Cell Biol
. 2018 Jun;
54:106-113.
PMID: 29890397
Cells use different means to communicate within and between tissues and thereby coordinate their behaviours. Following the initial observations of enigmatic long filopodia unrelated to cell movement, it became clear...
8.
Ober E, Lemaigre F
J Hepatol
. 2018 Jan;
68(5):1049-1062.
PMID: 29339113
Recent development of improved tools and methods to analyse tissues at the three-dimensional level has expanded our capacity to investigate morphogenesis of foetal liver. Here, we review the key morphogenetic...
9.
Wang S, Miller S, Ober E, Sadler K
Curr Top Dev Biol
. 2017 Mar;
124:161-195.
PMID: 28335859
The adult liver of most vertebrates is predominantly comprised of hepatocytes. However, these cells must work in concert with biliary, stellate, vascular, and immune cells to accomplish the vast array...
10.
Lonowski L, Narimatsu Y, Riaz A, Delay C, Yang Z, Niola F, et al.
Nat Protoc
. 2017 Feb;
12(3):581-603.
PMID: 28207001
This protocol describes methods for increasing and evaluating the efficiency of genome editing based on the CRISPR-Cas9 (clustered regularly interspaced short palindromic repeats-CRISPR-associated 9) system, transcription activator-like effector nucleases (TALENs)...