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Elizabeth R Haiderer

Explore the profile of Elizabeth R Haiderer including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 82
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Recent Articles
1.
Dechow S, Goyal R, Johnson B, Haiderer E, Abramovitch R
Infect Immun . 2025 Feb; 93(3):e0056824. PMID: 39964175
The (Mtb) two-component regulatory system PhoPR is implicated in pH sensing within the macrophage because it is strongly induced by acidic pH both and the macrophage phagosome. The carbonic anhydrase...
2.
Andringa R, Marinus N, Bunt D, Haiderer E, Abramovitch R, Brown C, et al.
Chem Sci . 2024 Jul; 15(27):10541-10546. PMID: 38994423
Dissectol A is a rearranged terpene glycoside isolated from several flowering plants. Starting from glucose, the densely functionalized bicyclic structure has been prepared site-selective oxidation and an intramolecular allylic alkylation...
3.
Williams J, Giletto M, Haiderer E, Aleiwi B, Krieger-Burke T, Ellsworth E, et al.
Microbiol Spectr . 2023 Dec; 12(1):e0367723. PMID: 38078724
MmpL3 is a protein that is required for the survival of bacteria that cause tuberculosis (TB) and nontuberculous mycobacterial (NTM) infections. This report describes the discovery and characterization of a...
4.
Eke I, Williams J, Haiderer E, Albrecht V, Murdoch H, Abdalla B, et al.
Antimicrob Agents Chemother . 2023 Aug; 67(9):e0047423. PMID: 37610224
Nitro-containing compounds have emerged as important agents in the control of tuberculosis (TB). From a whole-cell high-throughput screen for (Mtb) growth inhibitors, 10 nitro-containing compounds were prioritized for characterization and...
5.
Williams J, Haiderer E, Coulson G, Conner K, Ellsworth E, Chen C, et al.
Antimicrob Agents Chemother . 2019 Aug; 63(10). PMID: 31405862
The mycolate flippase MmpL3 has been the proposed target for multiple inhibitors with diverse chemical scaffolds. This diversity in chemical scaffolds has made it difficult to predict compounds that inhibit...
6.
Zheng H, Williams J, Coulson G, Haiderer E, Abramovitch R
Antimicrob Agents Chemother . 2018 Apr; 62(7). PMID: 29661875
Tuberculosis, caused by the intracellular pathogen , is a deadly disease that requires a long course of treatment. The emergence of drug-resistant strains has driven efforts to discover new small...
7.
Coulson G, Johnson B, Zheng H, Colvin C, Fillinger R, Haiderer E, et al.
Cell Chem Biol . 2017 Aug; 24(8):993-1004.e4. PMID: 28781126
Mycobacterium tuberculosis (Mtb) must sense and adapt to immune pressures such as acidic pH during pathogenesis. The goal of this study was to isolate compounds that inhibit acidic pH resistance,...