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Elizabeth C Bryda

Explore the profile of Elizabeth C Bryda including associated specialties, affiliations and a list of published articles. Areas
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Articles 56
Citations 823
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Recent Articles
1.
McNew J, Davis D, Grimsrud K, Bryda E
Comp Med . 2024 Aug; 74(3):173-178. PMID: 39107939
While rodents are used extensively for studying pain, there is a lack of reported direct comparisons of thermal and mechanical pain testing methods in rats of different genetic backgrounds. Understanding...
2.
Davis D, McNew J, Walls J, Bethune C, Oswalt P, Bryda E
J Vis Exp . 2024 Apr; (205). PMID: 38557598
Genome editing technology is widely used to produce genetically modified animals, including rats. Cytoplasmic or pronuclear injection of DNA repair templates and CRISPR-Cas reagents is the most common delivery method...
3.
McNew J, Davis D, Grimsrud K, Bryda E
J Am Assoc Lab Anim Sci . 2024 Mar; PMID: 38458616
While rodents are used extensively for studying pain, there is a lack of reported direct comparisons of thermal and mechanical pain testing methods in rats of different genetic backgrounds. Understanding...
4.
Derman R, Bryda E, Ferrario C
Behav Brain Res . 2023 Nov; 459:114768. PMID: 37984521
While sign-tracking, also known as autoshaping, has been studied for many decades, only recently has the tendency to show sign-tracking behavior been linked to the development and persistence of addiction....
5.
Davis D, McNew J, Maresca-Fichter H, Chen K, Telugu B, Bryda E
Front Genome Ed . 2023 Sep; 5:1256451. PMID: 37694158
Recent advances in CRISPR-Cas genome editing technology have been instrumental in improving the efficiency to produce genetically modified animal models. In this study we have combined four very promising approaches...
6.
Bryda E, Men H, Stone B
Methods Mol Biol . 2023 Mar; 2631:355-370. PMID: 36995677
The availability of reliable germline competent rat embryonic stem cell (ESC) lines that can be genetically manipulated provides an important tool for generating new rat models. Here we describe the...
7.
Men H, Davis D, Bryda E
Methods Mol Biol . 2023 Mar; 2631:341-353. PMID: 36995676
Rat germline-competent embryonic stem (ES) cell lines have been available since 2008, and rat models with targeted mutations have been successfully generated using ES cell-based genome targeting technology. This chapter...
8.
Davis D, Men H, Bryda E
Methods Mol Biol . 2023 Mar; 2631:267-276. PMID: 36995672
Genetic engineering in the rat has been revolutionized by the development of CRISPR-based genome editing tools. Conventional methods for inserting genome editing elements such as CRISPR/Cas9 reagents into rat zygotes...
9.
Men H, Amos-Landgraf J, Bryda E, Franklin C
Theriogenology . 2022 Dec; 198:69-74. PMID: 36563630
A modified KSOM for rat embryo culture (KSOM-R), which has enriched taurine, glycine, glutamic acid, and alanine, promoted rat embryo development in vitro. Since mice and rats share similar amino...
10.
Hummel D, Becks A, Men H, Bryda E, Glasco D, Chandrasekhar A
Development . 2022 Nov; 149(22). PMID: 36325991
In the developing hindbrain, facial branchiomotor (FBM) neurons migrate caudally from rhombomere 4 (r4) to r6 to establish the circuit that drives jaw movements. Although the mechanisms regulating initiation of...