Elianne P Bulthuis
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Explore the profile of Elianne P Bulthuis including associated specialties, affiliations and a list of published articles.
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7
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145
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Recent Articles
1.
de Jonge A, Csikos T, Eken M, Bulthuis E, Poddighe P, Roemer M, et al.
Int J Mol Sci
. 2024 Nov;
25(22).
PMID: 39596160
In B-cell malignancies, the overexpression of MYC is associated with poor prognosis, but its mechanism underlying resistance to immunochemotherapy remains less clear. In further investigations of this issue, we show...
2.
SMDT1 variants impair EMRE-mediated mitochondrial calcium uptake in patients with muscle involvement
Bulthuis E, Adjobo-Hermans M, de Potter B, Hoogstraten S, Wezendonk L, Tutakhel O, et al.
Biochim Biophys Acta Mol Basis Dis
. 2023 Jul;
1869(8):166808.
PMID: 37454773
Ionic calcium (Ca) is a key messenger in signal transduction and its mitochondrial uptake plays an important role in cell physiology. This uptake is mediated by the mitochondrial Ca uniporter...
3.
Bulthuis E, Dieteren C, Bergmans J, Berkhout J, Wagenaars J, van de Westerlo E, et al.
EMBO J
. 2023 Feb;
42(7):e108533.
PMID: 36825437
Macromolecules of various sizes induce crowding of the cellular environment. This crowding impacts on biochemical reactions by increasing solvent viscosity, decreasing the water-accessible volume and altering protein shape, function, and...
4.
Bulthuis E, Einer C, Distelmaier F, Groh L, van Emst-de Vries S, van de Westerlo E, et al.
Free Radic Biol Med
. 2022 Jun;
188:434-446.
PMID: 35718301
Attachment of cargo molecules to lipophilic triphenylphosphonium (TPP) cations is a widely applied strategy for mitochondrial targeting. We previously demonstrated that the vitamin E-derived antioxidant Trolox increases the levels of...
5.
Keating S, Groh L, van der Heijden C, Rodriguez H, Dos Santos J, Fanucchi S, et al.
Cell Rep
. 2020 Apr;
31(3):107548.
PMID: 32320649
Trained immunity confers a sustained augmented response of innate immune cells to a secondary challenge, via a process dependent on metabolic and transcriptional reprogramming. Because of its previous associations with...
6.
Bulthuis E, Adjobo-Hermans M, Willems P, Koopman W
Antioxid Redox Signal
. 2018 Sep;
30(18):2066-2109.
PMID: 30266077
In addition to their classical role in cellular ATP production, mitochondria are of key relevance in various (patho)physiological mechanisms including second messenger signaling, neuro-transduction, immune responses and death induction. Within...
7.
Vitali D, Sinzel M, Bulthuis E, Kolb A, Zabel S, Mehlhorn D, et al.
J Cell Sci
. 2018 Apr;
131(10).
PMID: 29661846
Tail-anchored (TA) proteins are anchored to their corresponding membrane via a single transmembrane segment (TMS) at their C-terminus. In yeast, the targeting of TA proteins to the endoplasmic reticulum (ER)...