Elena Torlai Triglia
Overview
Explore the profile of Elena Torlai Triglia including associated specialties, affiliations and a list of published articles.
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13
Citations
619
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Recent Articles
1.
Ding Q, Wu Y, Torlai Triglia E, Gommerman J, Subramanian A, Kuchroo V, et al.
bioRxiv
. 2023 Oct;
PMID: 37790513
B cells can express pro-inflammatory cytokines that promote a wide variety of immune responses. Here we show that B cells expressing the phosphatidylserine receptor TIM-4, preferentially express IL-17A, as well...
2.
Bod L, Kye Y, Shi J, Torlai Triglia E, Schnell A, Fessler J, et al.
Nature
. 2023 Jun;
619(7969):348-356.
PMID: 37344597
The role of B cells in anti-tumour immunity is still debated and, accordingly, immunotherapies have focused on targeting T and natural killer cells to inhibit tumour growth. Here, using high-throughput...
3.
Hodis E, Torlai Triglia E, Kwon J, Biancalani T, Zakka L, Parkar S, et al.
Science
. 2022 Apr;
376(6592):eabi8175.
PMID: 35482859
Establishing causal relationships between genetic alterations of human cancers and specific phenotypes of malignancy remains a challenge. We sequentially introduced mutations into healthy human melanocytes in up to five genes...
4.
Winick-Ng W, Kukalev A, Harabula I, Zea-Redondo L, Szabo D, Meijer M, et al.
Nature
. 2021 Nov;
599(7886):684-691.
PMID: 34789882
The three-dimensional (3D) structure of chromatin is intrinsically associated with gene regulation and cell function. Methods based on chromatin conformation capture have mapped chromatin structures in neuronal systems such as...
5.
Muus C, Luecken M, Eraslan G, Sikkema L, Waghray A, Heimberg G, et al.
Nat Med
. 2021 Mar;
27(3):546-559.
PMID: 33654293
Angiotensin-converting enzyme 2 (ACE2) and accessory proteases (TMPRSS2 and CTSL) are needed for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cellular entry, and their expression may shed light on viral...
6.
Bielecki P, Riesenfeld S, Hutter J, Torlai Triglia E, Kowalczyk M, Ricardo-Gonzalez R, et al.
Nature
. 2021 Feb;
592(7852):128-132.
PMID: 33536623
Tissue-resident innate lymphoid cells (ILCs) help sustain barrier function and respond to local signals. ILCs are traditionally classified as ILC1, ILC2 or ILC3 on the basis of their expression of...
7.
Skourti-Stathaki K, Torlai Triglia E, Warburton M, Voigt P, Bird A, Pombo A
Mol Cell
. 2019 Feb;
73(5):930-945.e4.
PMID: 30709709
R-loops are three-stranded nucleic acid structures that form during transcription, especially over unmethylated CpG-rich promoters of active genes. In mouse embryonic stem cells (mESCs), CpG-rich developmental regulator genes are repressed...
8.
Ferrai C, Torlai Triglia E, Risner-Janiczek J, Rito T, Rackham O, de Santiago I, et al.
Mol Syst Biol
. 2017 Oct;
13(10):946.
PMID: 29038337
Polycomb repression in mouse embryonic stem cells (ESCs) is tightly associated with promoter co-occupancy of RNA polymerase II (RNAPII) which is thought to prime genes for activation during early development....
9.
Kar G, Kim J, Kolodziejczyk A, Natarajan K, Torlai Triglia E, Mifsud B, et al.
Nat Commun
. 2017 Jun;
8(1):36.
PMID: 28652613
Polycomb repressive complexes (PRCs) are important histone modifiers, which silence gene expression; yet, there exists a subset of PRC-bound genes actively transcribed by RNA polymerase II (RNAPII). It is likely...
10.
Caglio G, Torlai Triglia E, Pombo A
Cell Stem Cell
. 2017 May;
20(5):573-575.
PMID: 28475876
Enhancers exist in different epigenetic states: active, primed, or poised. However, it is not yet understood how the different enhancer states influence gene activation. In this issue of Cell Stem...