Elena Poser
Overview
Explore the profile of Elena Poser including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
348
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Recent Articles
1.
Genovese I, Giamogante F, Barazzuol L, Battista T, Fiorillo A, Vicario M, et al.
Cell Death Dis
. 2020 Oct;
11(10):861.
PMID: 33060591
Dysregulation of calcium signaling is emerging as a key feature in the pathogenesis of neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD), and Huntington's disease (HD), and targeting...
2.
Poser E, Caous R, Gruneberg U, Barr F
J Cell Biol
. 2019 Dec;
219(2).
PMID: 31881080
Aurora kinases create phosphorylation gradients within the spindle during prometaphase and anaphase, thereby locally regulating factors that promote spindle organization, chromosome condensation and movement, and cytokinesis. We show that one...
3.
Getting out of mitosis: spatial and temporal control of mitotic exit and cytokinesis by PP1 and PP2A
Holder J, Poser E, Barr F
FEBS Lett
. 2019 Sep;
593(20):2908-2924.
PMID: 31494926
Here, we will review the evidence showing that mitotic exit is initiated by regulated proteolysis and then driven by the PPP family of phosphoserine/threonine phosphatases. Rapid APC/C and ubiquitin-dependent proteolysis...
4.
Poser E, Genovese I, Masciarelli S, Bellissimo T, Fazi F, Colotti G
Methods Mol Biol
. 2016 Dec;
1517:223-237.
PMID: 27924486
Surface plasmon resonance (SPR) is one of the most important techniques for the detection and the characterization of molecular interactions. SPR technology is a label-free approach for monitoring biomolecular interactions...
5.
Bellissimo T, Masciarelli S, Poser E, Genovese I, Del Rio A, Colotti G, et al.
Methods Mol Biol
. 2016 Dec;
1517:211-221.
PMID: 27924485
The development of small-molecule-based target therapy design for human disease and cancer is object of growing attention. Recently, specific microRNA (miRNA) mimicking compounds able to bind the miRNA-binding domain of...
6.
Cundell M, Hutter L, Bastos R, Poser E, Holder J, Mohammed S, et al.
J Cell Biol
. 2016 Aug;
214(5):539-54.
PMID: 27551054
PP2A-B55 is one of the major phosphatases regulating cell division. Despite its importance for temporal control during mitotic exit, how B55 substrates are recognized and differentially dephosphorylated is unclear. Using...
7.
Short peptides from leucyl-tRNA synthetase rescue disease-causing mitochondrial tRNA point mutations
Perli E, Fiorillo A, Giordano C, Pisano A, Montanari A, Grazioli P, et al.
Hum Mol Genet
. 2016 Jan;
25(5):903-15.
PMID: 26721932
Mutations in mitochondrial (mt) genes coding for mt-tRNAs are responsible for a range of syndromes, for which no effective treatment is available. We recently showed that the carboxy-terminal domain (Cterm)...
8.
Ilari A, Fiorillo A, Poser E, Lalioti V, Sundell G, Ivarsson Y, et al.
Sci Rep
. 2015 Nov;
5:16828.
PMID: 26577048
Sorcin is an essential penta-EF hand calcium binding protein, able to confer the multi-drug resistance phenotype to drug-sensitive cancer cells and to reduce Endoplasmic Reticulum stress and cell death. Sorcin...
9.
Ilari A, Fiorillo A, Baiocco P, Poser E, Angiulli G, Colotti G
Mini Rev Med Chem
. 2015 Mar;
15(3):243-52.
PMID: 25769972
Leishmaniasis is a neglected disease affecting more than 12 million people worldwide. The most used drugs are pentavalent antimonials that are very toxic and display the problem of drug resistance,...
10.
Colotti G, Poser E, Fiorillo A, Genovese I, Chiarini V, Ilari A
Molecules
. 2014 Sep;
19(9):13976-89.
PMID: 25197934
Sorcin is a penta-EF hand calcium binding protein, which participates in the regulation of calcium homeostasis in cells. Sorcin regulates calcium channels and exchangers located at the plasma membrane and...