Elena M Sanchez-Fernandez
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Explore the profile of Elena M Sanchez-Fernandez including associated specialties, affiliations and a list of published articles.
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26
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264
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Recent Articles
1.
Rocha G, Ramirez-Cardenas J, Carmen Padilla-Perez M, Walpole S, Nepravishta R, Isabel Garcia-Moreno M, et al.
Anal Chem
. 2024 Jan;
96(2):615-619.
PMID: 38165272
STD NMR spectroscopy is a powerful ligand-observed NMR tool for screening and characterizing the interactions of small molecules and low molecular weight fragments with a given macromolecule, identifying the main...
2.
Guerrero F, Carmona A, Vidal V, Franco A, Martin-Malo A, Sanchez-Fernandez E, et al.
Nanoscale Horiz
. 2023 Oct;
8(12):1700-1710.
PMID: 37819240
A selenium-containing metal-organic framework with remarkable antioxidant capacity and ROS-scavenging activity was constructed by a controlled encapsulation approach of a glycoconjugate mimetic, specifically a sp-iminoglycolipid bearing a selenoureido fragment (DSeU),...
3.
Carmen Padilla-Perez M, Sanchez-Fernandez E, Gonzalez-Bakker A, Puerta A, Padron J, Martin-Loro F, et al.
Eur J Med Chem
. 2023 May;
255:115390.
PMID: 37137247
The unique electronic properties of the fluorine atom make its strategic incorporation into a bioactive compound a very useful tool in the design of drugs with optimized pharmacological properties. In...
4.
Herrera-Gonzalez I, Thepaut M, Sanchez-Fernandez E, Di Maio A, Vives C, Rojo J, et al.
Chem Commun (Camb)
. 2022 Oct;
58(86):12086-12089.
PMID: 36219150
Selective DC-SIGN targeting . langerin might lead to anti-infective agents, given their counteracting effects upon infection by some pathogens. Here we show that multivalent sp-iminosugar-containing mannobioside analogs can achieve total...
5.
Gomez-Jaramillo L, Cano-Cano F, Sanchez-Fernandez E, Ortiz Mellet C, Garcia-Fernandez J, Alcala M, et al.
Int J Mol Sci
. 2022 Aug;
23(15).
PMID: 35955585
Inflammatory processes play a central role in the pathogenesis of diabetic nephropathy (DN) in the early stages of the disease. The authors demonstrate that the glycolipid mimetic ()-DS-ONJ is able...
6.
Sanchez-Fernandez E, Garcia-Hernandez R, Gamarro F, Arroba A, Aguilar-Diosdado M, Padron J, et al.
Molecules
. 2021 Dec;
26(24).
PMID: 34946583
sp-Iminosugar glycolipids (sp-IGLs) represent a consolidated family of glycoconjugate mimetics encompassing a monosaccharide-like glycone moiety with a pseudoamide-type nitrogen replacing the endocyclic oxygen atom of carbohydrates and an axially-oriented lipid...
7.
Cano-Cano F, Alcalde-Estevez E, Gomez-Jaramillo L, Iturregui M, Sanchez-Fernandez E, Garcia Fernandez J, et al.
Front Immunol
. 2021 Apr;
12:632132.
PMID: 33815384
Diabetic retinopathy (DR) is one of the most common complications of Diabetes Mellitus (DM) and is directly associated with inflammatory processes. Currently, neuro-inflammation is considered an early event in DR...
8.
Guillen-Poza P, Sanchez-Fernandez E, Artigas G, Garcia Fernandez J, Hinou H, Ortiz Mellet C, et al.
J Med Chem
. 2020 Jul;
63(15):8524-8533.
PMID: 32672464
In many human carcinomas, mucin-1 (MUC1) is overexpressed and aberrantly glycosylated, resulting in the exposure of previously hidden antigens. This generates new patient antibody profiles that can be used in...
9.
Herrera-Gonzalez I, Sanchez-Fernandez E, Sau A, Nativi C, Garcia Fernandez J, Galan M, et al.
J Org Chem
. 2020 Mar;
85(7):5038-5047.
PMID: 32159355
The first examples of iminosugar-type 2-deoxy(thio)glycoside mimetics are reported. The key step is the activation of a bicyclic iminoglycal carbamate to generate a highly reactive acyliminium cation. Cerium(IV) ammonium nitrate...
10.
Sanchez-Fernandez E, Garcia-Moreno M, Arroba A, Aguilar-Diosdado M, Padron J, Garcia-Hernandez R, et al.
Eur J Med Chem
. 2019 Aug;
182:111604.
PMID: 31425910
Immunomodulatory glycolipids, among which α-galactosylceramide (KRN7000) is an iconic example, have shown strong therapeutic potential in a variety of conditions ranging from cancer and infection to autoimmune or neurodegenerative diseases....