Elena B Okon
Overview
Explore the profile of Elena B Okon including associated specialties, affiliations and a list of published articles.
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Articles
29
Citations
752
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Recent Articles
1.
Skinnider M, Rogalski J, Tigchelaar S, Manouchehri N, Prudova A, Jackson A, et al.
Mol Cell Proteomics
. 2021 Jun;
20:100096.
PMID: 34129941
Despite the emergence of promising therapeutic approaches in preclinical studies, the failure of large-scale clinical trials leaves clinicians without effective treatments for acute spinal cord injury (SCI). These trials are...
2.
Streijger F, Kim K, So K, Manouchehri N, Shortt K, Okon E, et al.
J Neurotrauma
. 2021 May;
38(21):2937-2955.
PMID: 34011164
After acute traumatic spinal cord injury (SCI), the spinal cord can swell to fill the subarachnoid space and become compressed by the surrounding dura. In a porcine model of SCI,...
3.
Keung M, Streijger F, Herrity A, Ethridge J, Dougherty S, Aslan S, et al.
J Neurotrauma
. 2021 Jan;
38(9):1306-1326.
PMID: 33499736
There is an increasing need to develop approaches that will not only improve the clinical management of neurogenic lower urinary tract dysfunction (NLUTD) after spinal cord injury (SCI), but also...
4.
Cheung A, Streijger F, So K, Okon E, Manouchehri N, Shortt K, et al.
J Neurotrauma
. 2020 Apr;
37(15):1696-1707.
PMID: 32233727
Current practice guidelines for acute spinal cord injury (SCI) recommend augmenting mean arterial blood pressure (MAP) for the first 7 days post-injury. After SCI, the cord may be compressed by...
5.
Kim K, Streijger F, Manouchehri N, So K, Shortt K, Okon E, et al.
J Korean Neurosurg Soc
. 2018 Sep;
61(5):539-547.
PMID: 30196652
Traumatic spinal cord injury (SCI) research has recently focused on the use of rat and mouse models for in vivo SCI experiments. Such small rodent SCI models are invaluable for...
6.
Streijger F, So K, Manouchehri N, Gheorghe A, Okon E, Chan R, et al.
J Neurotrauma
. 2018 Jan;
35(12):1345-1357.
PMID: 29338544
Current clinical guidelines recommend elevating the mean arterial blood pressure (MAP) to increase spinal cord perfusion in patients with acute spinal cord injury (SCI). This is typically achieved with vasopressors...
7.
Streijger F, So K, Manouchehri N, Tigchelaar S, Lee J, Okon E, et al.
J Neurotrauma
. 2017 Aug;
34(24):3336-3350.
PMID: 28844181
Traumatic spinal cord injury (SCI) triggers many perturbations within the injured cord, such as decreased perfusion, reduced tissue oxygenation, increased hydrostatic pressure, and disrupted bioenergetics. While much attention is directed...
8.
Streijger F, Lee J, Manouchehri N, Melnyk A, Chak J, Tigchelaar S, et al.
J Neurotrauma
. 2016 May;
33(24):2217-2226.
PMID: 27214588
In the military environment, injured soldiers undergoing medical evacuation via helicopter or mine-resistant ambush-protected vehicle (MRAP) are subjected to vibration and shock inherent to the transport vehicle. We conducted the...
9.
Streijger F, Lee J, Manouchehri N, Okon E, Tigchelaar S, Anderson L, et al.
J Neurotrauma
. 2016 Apr;
33(24):2202-2216.
PMID: 27125815
A porcine model of spinal cord injury (SCI) was used to evaluate the neuroprotective effects of magnesium chloride (MgCl) within a polyethylene glycol (PEG) formulation, called "AC105" (Acorda Therapeutics Inc.,...
10.
Streijger F, Lee J, Chak J, Dressler D, Manouchehri N, Okon E, et al.
J Neurotrauma
. 2015 Jan;
32(12):908-21.
PMID: 25567669
Whole-body vibration has been identified as a potential stressor to spinal cord injury (SCI) patients during pre-hospital transportation. However, the effect that such vibration has on the acutely injured spinal...