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Elena Abramova

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Articles 18
Citations 190
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Recent Articles
1.
Meshanni J, Stevenson E, Zhang D, Sun R, Ona N, Reagan E, et al.
Nat Commun . 2025 Feb; 16(1):1806. PMID: 39984450
Current clinical strategies for the delivery of pulmonary therapeutics to the lung are primarily targeted to the upper portions of the airways, such as treatment with nebulized instillation and inhalation....
2.
Abramova E, Shapagina N, Artemiev G, Safonov A
Biology (Basel) . 2025 Jan; 13(12. PMID: 39765753
This paper presents the results of microbial corrosion tests on M0-grade copper under conditions simulating a geological repository for radioactive waste at the Yeniseisky site (Krasnoyarsk Krai, Russia). The work...
3.
Atochina-Vasserman E, Meshanni J, Stevenson E, Zhang D, Sun R, Ona N, et al.
Res Sq . 2024 Jul; PMID: 39041040
Current clinical strategies for the delivery of pulmonary therapeutics to the lung are primarily targeted to the upper portions of the airways. However, targeted delivery to the lower regions of...
4.
Smith L, Abramova E, Vayas K, Rodriguez J, Gelfand-Titiyevksiy B, Roepke T, et al.
Toxicol Sci . 2024 Jun; 201(1):103-117. PMID: 38897669
Macrophages play a key role in ozone-induced lung injury by regulating both the initiation and resolution of inflammation. These distinct activities are mediated by pro-inflammatory and anti-inflammatory/proresolution macrophages which sequentially...
5.
Radbel J, Meshanni J, Vayas K, Le-Hoang O, Abramova E, Zhou P, et al.
Toxicol Sci . 2024 May; 200(2):299-311. PMID: 38749002
Recent studies have identified exposure to environmental levels of ozone as a risk factor for the development of acute respiratory distress syndrome (ARDS), a severe form of acute lung injury...
6.
Gutierrez B, Aggarwal T, Erguven H, Stone M, Guo C, Bellomo A, et al.
iScience . 2023 Dec; 26(12):108567. PMID: 38144454
Lipid membranes and lipid-rich organelles are targets of peroxynitrite (ONOO), a highly reactive species generated under nitrative stress. We report a membrane-localized phospholipid () that allows the detection of ONOO...
7.
Smith L, Gow A, Abramova E, Vayas K, Guo C, Noto J, et al.
Toxicol Sci . 2023 May; 194(1):109-119. PMID: 37202362
Exposure to ozone causes decrements in pulmonary function, a response associated with alterations in lung lipids. Pulmonary lipid homeostasis is dependent on the activity of peroxisome proliferator activated receptor gamma...
8.
Taylor S, Murray A, Francis M, Abramova E, Guo C, Laskin D, et al.
Toxicol Appl Pharmacol . 2022 Oct; 457:116281. PMID: 36244437
Acute exposure to ozone causes oxidative stress, characterized by increases in nitric oxide (NO) and other reactive nitrogen species in the lung. NO has been shown to modify thiols generating...
9.
Sunil V, Vayas K, Radbel J, Abramova E, Gow A, Laskin J, et al.
Toxicol Appl Pharmacol . 2022 Sep; 456:116257. PMID: 36174670
Nitrogen mustard (NM) is a cytotoxic vesicant known to cause acute lung injury which progresses to fibrosis. Alveolar Type II cells are primarily responsible for surfactant production; they also play...
10.
Stevenson E, Wilkinson M, Abramova E, Guo C, Gow A
J Pharmacol Exp Ther . 2022 Aug; 382(3):356-365. PMID: 35970601
Acute lung injury (ALI) is characterized by epithelial damage, barrier dysfunction, and pulmonary edema. Macrophage activation and failure to resolve play a role in ALI; thus, macrophage phenotype modulation is...