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Andrew J Gow

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Articles 112
Citations 2291
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Recent Articles
1.
Lee J, Meshanni J, Vayas K, Vayas K, Sunil V, Sunil V, et al.
Toxicol Sci . 2025 Jan; 204(1):70-78. PMID: 39798125
Ozone is an urban air pollutant known to cause lung injury and altered function. Using established models of acute (0.8 ppm, 3 h) and episodic (1.5 ppm, 2 h, 2...
2.
Lu F, Gupta D, Fiedler N, Satish U, Black K, Legard A, et al.
Environ Health Perspect . 2024 Oct; 132(10):107702. PMID: 39466336
No abstract available.
3.
Aggarwal T, Bellomo A, Stevenson E, Herbert J, Laskin D, Gow A, et al.
STAR Protoc . 2024 Aug; 5(3):103268. PMID: 39215997
Detection of nitrative stress is crucial to understanding redox signaling and pathophysiology. Dysregulated nitrative stress, which generates high levels of peroxynitrite, can damage lipid membranes and cause activation of proinflammatory...
4.
Smith L, Abramova E, Vayas K, Rodriguez J, Gelfand-Titiyevksiy B, Roepke T, et al.
Toxicol Sci . 2024 Jun; 201(1):103-117. PMID: 38897669
Macrophages play a key role in ozone-induced lung injury by regulating both the initiation and resolution of inflammation. These distinct activities are mediated by pro-inflammatory and anti-inflammatory/proresolution macrophages which sequentially...
5.
Radbel J, Meshanni J, Vayas K, Le-Hoang O, Abramova E, Zhou P, et al.
Toxicol Sci . 2024 May; 200(2):299-311. PMID: 38749002
Recent studies have identified exposure to environmental levels of ozone as a risk factor for the development of acute respiratory distress syndrome (ARDS), a severe form of acute lung injury...
6.
Bellomo A, Herbert J, Kudlak M, Laskin J, Gow A, Laskin D
Toxicol Appl Pharmacol . 2024 Apr; 486:116941. PMID: 38677601
Nitrogen mustard (NM; mechlorethamine) is a cytotoxic vesicant known to cause acute lung injury which can progress to chronic disease. Due to the complex nature of NM injury, it has...
7.
Malaviya R, Meshanni J, Sunil V, Venosa A, Guo C, Abramova E, et al.
Toxicol Appl Pharmacol . 2024 Mar; 485:116908. PMID: 38513841
Nitrogen mustard (NM) is a toxic vesicant that causes acute injury to the respiratory tract. This is accompanied by an accumulation of activated macrophages in the lung and oxidative stress...
8.
Malin S, Remchak M, Heiston E, Battillo D, Gow A, Shah A, et al.
Diabetes Obes Metab . 2024 Jan; 26(5):1582-1592. PMID: 38246697
Aim: Chronotype reflects a circadian rhythmicity that regulates endothelial function. While the morning chronotype (MORN) usually has low cardiovascular disease risk, no study has examined insulin action on endothelial function...
9.
Gutierrez B, Aggarwal T, Erguven H, Stone M, Guo C, Bellomo A, et al.
iScience . 2023 Dec; 26(12):108567. PMID: 38144454
Lipid membranes and lipid-rich organelles are targets of peroxynitrite (ONOO), a highly reactive species generated under nitrative stress. We report a membrane-localized phospholipid () that allows the detection of ONOO...
10.
Remchak M, Dosik J, Pappas G, Gow A, Shah A, Malin S
Am J Physiol Heart Circ Physiol . 2023 Jul; 325(4):H635-H644. PMID: 37505468
Exaggerated exercise blood pressure (BP) is linked to cardiovascular disease (CVD). Although evening chronotypes have greater CVD risk than morning (Morn) types, it is unknown if exercise BP differs in...