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Eleanor J Guest

Explore the profile of Eleanor J Guest including associated specialties, affiliations and a list of published articles. Areas
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1.
Guest E, Rowland-Yeo K, Rostami-Hodjegan A, Tucker G, Houston J, Galetin A
Br J Clin Pharmacol . 2010 Dec; 71(1):72-87. PMID: 21143503
What Is Already Known About This Subject: The prediction of drug-drug interactions (DDIs) from in vitro data usually utilizes an average dosing interval estimate of inhibitor concentration in an equation-based...
2.
Guest E, Aarons L, Houston J, Rostami-Hodjegan A, Galetin A
Drug Metab Dispos . 2010 Nov; 39(2):170-3. PMID: 21036951
Current assessment of drug-drug interaction (DDI) prediction success is based on whether predictions fall within a two-fold range of the observed data. This strategy results in a potential bias toward...