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Ekaterina Pylaeva

Explore the profile of Ekaterina Pylaeva including associated specialties, affiliations and a list of published articles. Areas
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Articles 18
Citations 330
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Recent Articles
1.
Park S, Pylaeva E, Bhuria V, Gambardella A, Schiavoni G, Mougiakakos D, et al.
Mol Cancer . 2025 Mar; 24(1):69. PMID: 40050933
Cancer-associated myeloid cells due to their plasticity play dual roles in both promoting and inhibiting tumor progression. Myeloid cells with immunosuppressive properties play a critical role in anti-cancer immune regulation....
2.
Droege F, Konig J, Lang K, Jablonska J, Pylaeva E, Huckenbeck C, et al.
J Clin Med . 2024 Jul; 13(13). PMID: 38999318
: Hereditary hemorrhagic telangiectasia (HHT) is a rare disorder characterized by dilated blood vessels. Different immunological changes have been described in these patients. In this study, the predisposition of patients...
3.
Pylaeva E, Jablonska J
Signal Transduct Target Ther . 2023 Nov; 8(1):421. PMID: 37935662
No abstract available.
4.
Duerig I, Pylaeva E, Ozel I, Wainwright S, Thiel I, Bordbari S, et al.
J Leukoc Biol . 2023 Aug; 114(6):639-650. PMID: 37555392
The transforming growth factor β (TGF-β)/ALK1/ENG signaling pathway maintains quiescent state of endothelial cells, but at the same time, it regulates neutrophil functions. Importantly, mutations of this pathway lead to...
5.
Antoni A, Pylaeva E, Budeus B, Jablonska J, Klein-Hitpass L, Dudda M, et al.
Front Immunol . 2022 Sep; 13:945409. PMID: 36148245
Sepsis is associated with profound immune dysregulation that increases the risk for life-threatening secondary infections: Dendritic cells (DCs) undergo functional reprogramming due to yet unknown changes during differentiation in the...
6.
Pylaeva E, Korschunow G, Spyra I, Bordbari S, Siakaeva E, Ozel I, et al.
Cell Rep . 2022 Aug; 40(7):111171. PMID: 35977505
Tumor-draining lymph nodes (LNs) play a crucial role during cancer spread and in initiation of anti-cancer adaptive immunity. Neutrophils form a substantial population of cells in LNs with poorly understood...
7.
Hussain T, Domnich M, Bordbari S, Pylaeva E, Siakaeva E, Spyra I, et al.
Front Immunol . 2022 Jul; 13:878959. PMID: 35833131
Tumor-draining lymph nodes (TDLNs) are the first organs where the metastatic spread of different types of cancer, including head and neck cancer (HNC), occurs and have therefore high prognostic relevance....
8.
Ozel I, Duerig I, Domnich M, Lang S, Pylaeva E, Jablonska J
Cancers (Basel) . 2022 Feb; 14(3). PMID: 35158807
Angiogenesis, the formation of new blood vessels from already existing vasculature, is tightly regulated by pro- and anti-angiogenic stimuli and occurs under both physiological and pathological conditions. Tumor angiogenesis is...
9.
Bordbari S, Morchen B, Pylaeva E, Siakaeva E, Spyra I, Domnich M, et al.
Int J Cancer . 2021 Nov; 150(7):1198-1211. PMID: 34751438
Angiogenesis plays an important role during tumor growth and metastasis. We could previously show that Type I interferon (IFN)-deficient tumor-associated neutrophils (TANs) show strong pro-angiogenic activity, and stimulate tumor angiogenesis...
10.
Pylaeva E, Ozel I, Squire A, Spyra I, Wallner C, Korek M, et al.
Cancers (Basel) . 2021 Jul; 13(12). PMID: 34205654
The role of neutrophils during cancer formation and elimination is diverse. Here, for the first time, we investigate neutrophil helper cells (N), their influence on B cell activity in the...