Eirini Maniou
Overview
Explore the profile of Eirini Maniou including associated specialties, affiliations and a list of published articles.
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15
Citations
85
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Recent Articles
1.
Santos C, Marshall A, Murray A, Metcalfe K, Narayan P, de Castro S, et al.
Elife
. 2024 Dec;
12.
PMID: 39636098
Primary and secondary neurulation - processes that form the spinal cord - are incompletely understood in humans, largely due to the challenge of accessing neurulation-stage embryos (3-7 weeks post-conception). Here,...
2.
Perez-Verdugo F, Maniou E, Galea G, Banerjee S
bioRxiv
. 2024 Nov;
PMID: 39605583
Cell patterning is essential for organized tissue development, enabling precise geometric arrangement of cells, body axis establishment and developmental timing. Here we investigate the role of physical forces and mechanical...
3.
Birtele M, Cerise M, Djenoune L, Kale G, Maniou E, Prahl L, et al.
Development
. 2024 Oct;
151(19).
PMID: 39369305
In this Perspective, our 2024 Pathway to Independence Fellows provide their thoughts on the future of their field. Covering topics as diverse as plant development, tissue engineering and adaptation to...
4.
Maniou E, Todros S, Urciuolo A, Moulding D, Magnussen M, Ampartzidis I, et al.
Nat Mater
. 2024 Jul;
23(11):1575-1581.
PMID: 38969783
Morphogenesis requires embryonic cells to generate forces and perform mechanical work to shape their tissues. Incorrect functioning of these force fields can lead to congenital malformations. Understanding these dynamic processes...
5.
Zekavat A, Lioliou G, Roche I Morgo O, Maughan Jones C, Galea G, Maniou E, et al.
Phys Med Biol
. 2024 Apr;
69(10).
PMID: 38631365
To report on a micro computed tomography (micro-CT) system capable of x-ray phase contrast imaging and of increasing spatial resolution at constant magnification.The micro-CT system implements the edge illumination (EI)...
6.
Maniou E, Farah F, Marshall A, Crane-Smith Z, Krstevski A, Stathopoulou A, et al.
Development
. 2023 Sep;
150(19).
PMID: 37756583
Closed spinal dysraphisms are poorly understood malformations classified as neural tube (NT) defects. Several, including terminal myelocystocele, affect the distal spine. We have previously identified a NT closure-initiating point, Closure...
7.
Ampartzidis I, Efstathiou C, Paonessa F, Thompson E, Wilson T, McCann C, et al.
Dev Biol
. 2022 Dec;
494:60-70.
PMID: 36509125
Neuroepithelial cells balance tissue growth requirement with the morphogenetic imperative of closing the neural tube. They apically constrict to generate mechanical forces which elevate the neural folds, but are thought...
8.
Marshall A, Maniou E, Moulding D, Greene N, Copp A, Galea G
Methods Mol Biol
. 2022 Feb;
2438:217-230.
PMID: 35147945
Laser ablation is routinely performed to infer mechanical tension in cells and tissues. Here we describe our method of two-photon laser ablation at the cellular and tissue level in mouse...
9.
Galea G, Maniou E, Edwards T, Marshall A, Ampartzidis I, Greene N, et al.
Nat Commun
. 2021 May;
12(1):3301.
PMID: 34050195
No abstract available.
10.
Maniou E, Staddon M, Marshall A, Greene N, Copp A, Banerjee S, et al.
Proc Natl Acad Sci U S A
. 2021 May;
118(19).
PMID: 33941697
Gap closure is a common morphogenetic process. In mammals, failure to close the embryonic hindbrain neuropore (HNP) gap causes fatal anencephaly. We observed that surface ectoderm cells surrounding the mouse...