Einav Nili Gal-Yam
Overview
Explore the profile of Einav Nili Gal-Yam including associated specialties, affiliations and a list of published articles.
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Articles
33
Citations
2065
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Recent Articles
21.
Zundelevich A, Dadiani M, Kahana-Edwin S, Itay A, Sella T, Gadot M, et al.
Breast Cancer Res
. 2020 Feb;
22(1):16.
PMID: 32014063
Background: Emerging mutations in the ESR1 gene that encodes for the estrogen receptor (ER) are associated with resistance to endocrine therapy. ESR1 mutations rarely exist in primary tumors (~ 1%)...
22.
Bossel Ben-Moshe N, Gilad S, Perry G, Benjamin S, Balint-Lahat N, Pavlovsky A, et al.
BMC Genomics
. 2018 Jun;
19(1):419.
PMID: 29848287
Background: The main bottleneck for genomic studies of tumors is the limited availability of fresh frozen (FF) samples collected from patients, coupled with comprehensive long-term clinical follow-up. This shortage could...
23.
Dadiani M, Bossel Ben-Moshe N, Paluch-Shimon S, Perry G, Balint N, Marin I, et al.
Clin Cancer Res
. 2016 Mar;
22(14):3651-62.
PMID: 26957561
Purpose: Molecular evolution of tumors during progression, therapy, and metastasis is a major clinical challenge and the main reason for resistance to therapy. We hypothesized that microRNAs (miRNAs) that exhibit...
24.
Activation-Induced Cytidine Deaminase Links Ovulation-Induced Inflammation and Serous Carcinogenesis
Sapoznik S, Bahar-Shany K, Brand H, Pinto Y, Gabay O, Glick-Saar E, et al.
Neoplasia
. 2016 Mar;
18(2):90-9.
PMID: 26936395
In recent years, the notion that ovarian carcinoma results from ovulation-induced inflammation of the fallopian tube epithelial cells (FTECs) has gained evidence. However, the mechanistic pathway for this process has...
25.
Omer D, Harari-Steinberg O, Buzhor E, Metsuyanim S, Pleniceanu O, Zundelevich A, et al.
Cell Reprogram
. 2013 Jul;
15(4):281-92.
PMID: 23841748
Recent studies have suggested that epigenetic modulation with chromatin-modifying agents can induce stemness and dedifferentiation and increase developmental plasticity. For instance, valproic acid (VPA), a histone deacetylase (HDAC) inhibitor, has...
26.
Landan G, Mendelson Cohen N, Mukamel Z, Bar A, Molchadsky A, Brosh R, et al.
Nat Genet
. 2012 Oct;
44(11):1207-14.
PMID: 23064413
DNA methylation has been comprehensively profiled in normal and cancer cells, but the dynamics that form, maintain and reprogram differentially methylated regions remain enigmatic. Here, we show that methylation patterns...
27.
Rubinek T, Shulman M, Israeli S, Bose S, Avraham A, Zundelevich A, et al.
Breast Cancer Res Treat
. 2011 Nov;
133(2):649-57.
PMID: 22042362
Klotho is a single pass transmembrane protein, associated with premature aging. We identified tumor suppressor activities for klotho, associated with reduced expression in breast cancer. We now aimed to analyze...
28.
Nili Gal-Yam E, Egger G, Iniguez L, Holster H, Einarsson S, Zhang X, et al.
Proc Natl Acad Sci U S A
. 2008 Aug;
105(35):12979-84.
PMID: 18753622
Epigenetic reprogramming is commonly observed in cancer, and is hypothesized to involve multiple mechanisms, including DNA methylation and Polycomb repressive complexes (PRCs). Here we devise a new experimental and analytical...
29.
Shaklai S, Somech R, Nili Gal-Yam E, Deshet-Unger N, Moshitch-Moshkovitz S, Hirschberg K, et al.
Eur J Cell Biol
. 2008 Apr;
87(5):267-78.
PMID: 18403046
Proteins of the nuclear envelope have been implicated as participating in gene silencing. BAF, a DNA- and LEM domain-binding protein, has been suggested to link chromatin to the nuclear envelope....
30.
Lin J, Jeong S, Liang G, Takai D, Fatemi M, Tsai Y, et al.
Cancer Cell
. 2007 Nov;
12(5):432-44.
PMID: 17996647
Epigenetic silencing of tumor suppressor genes is generally thought to involve DNA cytosine methylation, covalent modifications of histones, and chromatin compaction. Here, we show that silencing of the three transcription...