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Eileen S Carpenter

Explore the profile of Eileen S Carpenter including associated specialties, affiliations and a list of published articles. Areas
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Articles 27
Citations 1354
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Recent Articles
1.
Valvo V, Zhang Q, Jiang L, Holcomb E, Pearson A, Edmunds A, et al.
Mol Cancer Ther . 2024 Dec; :OF1-OF16. PMID: 39688341
PARP inhibitors sensitize pancreatic ductal adenocarcinoma (PDAC) to radiation by inducing DNA damage and replication stress. These mechanisms also have the potential to enhance radiation-induced type I interferon (T1IFN)-mediated antitumoral...
2.
Bonilla M, Radyk M, Perricone M, Elhossiny A, Harold A, Medina-Cabrera P, et al.
JCI Insight . 2024 Sep; 9(18). PMID: 39315547
Pancreatic cancer, one of the deadliest human malignancies, is characterized by a fibro-inflammatory tumor microenvironment and wide array of metabolic alterations. To comprehensively map metabolism in a cell type-specific manner,...
3.
Carpenter E, Vendramini-Costa D, Hasselluhn M, Maitra A, Olive K, Cukierman E, et al.
Cancer Res . 2024 Sep; 84(21):3505-3508. PMID: 39283867
Pancreatic ductal adenocarcinoma is a deadly disease and is projected to become the second leading cause of cancer-related death by 2030. A major hallmark is the exuberant host response comprising...
4.
Donahue K, Watkoske H, Kadiyala P, Du W, Brown K, Scales M, et al.
Cancer Discov . 2024 Jul; 14(10):1964-1989. PMID: 38958646
Pancreatic cancer is characterized by an extensive fibroinflammatory microenvironment. During carcinogenesis, normal stromal cells are converted to cytokine-high cancer-associated fibroblasts (CAF). The mechanisms underlying this conversion, including the regulation and...
5.
Chalhoub J, Hawa F, Grantham T, Lester J, Carpenter E, Mendoza-Ladd A, et al.
Gastrointest Endosc . 2024 Jun; 100(4):595-604.e8. PMID: 38852683
Background And Aims: The optimal number of passes to maximize the diagnostic ability of EUS fine-needle biopsy (FNB) of solid pancreatic masses (SPMs) is not well known. We conducted a...
6.
Vargas A, Dutta P, Carpenter E, Machicado J
Diagnostics (Basel) . 2024 Mar; 14(5). PMID: 38473035
Pancreatic cancer is on the rise and expected to become the second leading cause of cancer-related death by 2030. Up to a one-fifth of pancreatic cancers may arise from mucinous...
7.
Vilela A, Quingalahua E, Vargas A, Hawa F, Shannon C, Carpenter E, et al.
Clin Gastroenterol Hepatol . 2024 Feb; 22(9):1798-1809.e6. PMID: 38423346
Background & Aims: Understanding the burden of pancreatic cystic lesions (PCLs) in the general population is important for clinicians and policymakers. In this systematic review, we sought to estimate the...
8.
Yan W, Menjivar R, Bonilla M, Steele N, Kemp S, Du W, et al.
Cancer Immunol Res . 2023 Nov; 12(1):91-106. PMID: 37931247
Pancreatic ductal adenocarcinoma (PDA) continues to have a dismal prognosis. The poor survival of patients with PDA has been attributed to a high rate of early metastasis and low efficacy...
9.
Carpenter E, Kadiyala P, Elhossiny A, Kemp S, Li J, Steele N, et al.
Clin Cancer Res . 2023 Oct; 30(11):2497-2513. PMID: 37851080
Purpose: Pancreatic ductal adenocarcinoma (PDAC) is generally divided in two subtypes, classical and basal. Recently, single-cell RNA sequencing has uncovered the coexistence of basal and classical cancer cells, as well...
10.
Nwosu Z, Ward M, Sajjakulnukit P, Poudel P, Ragulan C, Kasperek S, et al.
Nature . 2023 May; 618(7963):151-158. PMID: 37198494
Pancreatic ductal adenocarcinoma (PDA) is a lethal disease notoriously resistant to therapy. This is mediated in part by a complex tumour microenvironment, low vascularity, and metabolic aberrations. Although altered metabolism...