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» Authors » Effie Y H Nomicos

Effie Y H Nomicos

Explore the profile of Effie Y H Nomicos including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 7
Citations 117
Followers 0
Related Specialties
Pharmacology
General Medicine
Hematology
Top 10 Co-Authors
Andrea A Berry
Hector H Garcia
Catherine Cox
John Horton
Thanh Bach
Mark A Travassos
Matthew B Laurens
Ellen E Codd
Annie X Mo
Marcela F Pasetti
Published In
Antimicrob Agents Chemother
Blood
Vaccine
Holist Nurs Pract
Sci Transl Med
Affiliations
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Recent Articles
1.
Recombinant Full-length Plasmodium falciparum Circumsporozoite Protein-Based Vaccine Adjuvanted With Glucopyranosyl Lipid A-Liposome Quillaja saponaria 21: Results of Phase 1 Testing With Malaria Challenge
Friedman-Klabanoff D, Berry A, Travassos M, Shriver M, Cox C, Butts J, et al.
J Infect Dis . 2024 Feb; 229(6):1883-1893. PMID: 38330357
Background: Malaria is preventable yet causes >600 000 deaths annually. RTS,S, the first marketed malaria vaccine, has modest efficacy, but improvements are needed for eradication. Methods: We conducted an open-label,...
2.
Repeated infection in humans drives the clonal expansion of an adaptive γδ T cell repertoire
von Borstel A, Chevour P, Arsovski D, Krol J, Howson L, Berry A, et al.
Sci Transl Med . 2021 Dec; 13(622):eabe7430. PMID: 34851691
Repeated infections drive the development of clinical immunity to malaria in humans; however, the immunological mechanisms that underpin this response are only partially understood. We investigated the impact of repeated...
3.
Low dose recombinant full-length circumsporozoite protein-based Plasmodium falciparum vaccine is well-tolerated and highly immunogenic in phase 1 first-in-human clinical testing
Friedman-Klabanoff D, Berry A, Travassos M, Cox C, Zhou Y, Mo A, et al.
Vaccine . 2021 Jan; 39(8):1195-1200. PMID: 33494963
Plasmodium falciparum circumsporozoite protein (CSP) is a major sporozoite surface protein and a key target of pre-erythrocytic malaria subunit vaccines. A full-length recombinant CSP (rCSP) based strategy could be advantageous,...
4.
Pharmacokinetics, Safety, and Tolerability of Oxfendazole in Healthy Adults in an Open-Label Phase 1 Multiple Ascending Dose and Food Effect Study
Bach T, Galbiati S, Kennedy J, Deye G, Nomicos E, Codd E, et al.
Antimicrob Agents Chemother . 2020 Aug; 64(11). PMID: 32816721
Neurocysticercosis and trichuriasis are difficult-to-treat parasitic infections that affect more than 1.5 billion people worldwide. Oxfendazole, a potent broad-spectrum benzimidazole anthelmintic approved for use in veterinary medicine, has shown substantial...
5.
Pharmacokinetics, Safety, and Tolerability of Oxfendazole in Healthy Volunteers: a Randomized, Placebo-Controlled First-in-Human Single-Dose Escalation Study
An G, Murry D, Gajurel K, Bach T, Deye G, Stebounova L, et al.
Antimicrob Agents Chemother . 2019 Feb; 63(4). PMID: 30745383
Cysticercosis is a parasitic disease that frequently involves the human central nervous system (CNS), and current treatment options are limited. Oxfendazole, a veterinary medicine belonging to the benzimidazole family of...
6.
Myrrh: medical marvel or myth of the Magi?
Nomicos E
Holist Nurs Pract . 2007 Nov; 21(6):308-23. PMID: 17978635
Since antiquity, the genus Commiphora is composed of more than 200 species, and has been exploited as a natural drug to treat pain, skin infections, inflammatory conditions, diarrhea, and periodontal...
7.
Gene therapy improves immune function in preadolescents with X-linked severe combined immunodeficiency
Chinen J, Davis J, de Ravin S, Hay B, Hsu A, Linton G, et al.
Blood . 2007 Mar; 110(1):67-73. PMID: 17369490
Retroviral gene therapy can restore immunity to infants with X-linked severe combined immunodeficiency (XSCID) caused by mutations in the IL2RG gene encoding the common gamma chain (gammac) of receptors for...