Edwin W Lai
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Explore the profile of Edwin W Lai including associated specialties, affiliations and a list of published articles.
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Articles
42
Citations
1196
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Recent Articles
1.
Fackler M, Tulac S, Venkatesan N, Aslam A, de Guzman T, Mercado-Rodriguez C, et al.
Cancer Res Commun
. 2022 Sep;
2(6):391-401.
PMID: 36046124
Current molecular liquid biopsy assays to detect recurrence or monitor response to treatment require sophisticated technology, highly trained personnel, and a turnaround time of weeks. We describe the development and...
2.
Li J, Downs B, Cope L, Fackler M, Zhang X, Song C, et al.
NPJ Breast Cancer
. 2021 Jul;
7(1):89.
PMID: 34234148
Preoperative staging of suspicious axillary lymph nodes (ALNs) allows patients to be triaged to ALN dissection or to sentinel lymph node biopsy (SLNB). Ultrasound-guided fine needle aspiration (FNA) and cytology...
3.
Filipits M, Preusser M, Hainfellner J, Spiegl-Kreinecker S, Berghoff A, Lai E, et al.
Anticancer Res
. 2020 Oct;
40(11):6229-6236.
PMID: 33109560
Background/aim: To compare the GeneXpert® O6-methylguanine DNA methyltransferase (MGMT) methylation prototype (GX MGMT) assay with pyrosequencing in glioblastomas. Materials And Methods: The MGMT methylation status was retrospectively assessed in formalin-fixed...
4.
Gupta S, McCann L, Chan Y, Lai E, Wei W, Wong P, et al.
J Immunother Cancer
. 2019 Sep;
7(1):254.
PMID: 31533832
Background: In melanoma, there is no companion diagnostic test to predict response to programmed cell death 1 (PD-1) axis immune checkpoint inhibitor (ICI) therapy. In the adjuvant setting, only one...
5.
Downs B, Mercado-Rodriguez C, Cimino-Mathews A, Chen C, Yuan J, Van Den Berg E, et al.
Clin Cancer Res
. 2019 Jul;
25(21):6357-6367.
PMID: 31300453
Purpose: An unmet need in low-resource countries is an automated breast cancer detection assay to prioritize women who should undergo core breast biopsy and pathologic review. Therefore, we sought to...
6.
Wasserman B, Carvajal-Hausdorf D, Ho K, Wong W, Wu N, Chu V, et al.
Lab Invest
. 2017 Sep;
97(12):1521-1526.
PMID: 28892092
Historically, mRNA measurements have been tested on several commercially available platforms, but none have gained broad acceptance for assessment of HER2. An mRNA measurement, as a continuous value, has the...
7.
Moussouttas M, Lai E, Huynh T, James J, Stocks-Dietz C, Dombrowski K, et al.
J Clin Neurosci
. 2013 Oct;
21(2):256-62.
PMID: 24119956
Subarachnoid hemorrhage (SAH) is accompanied by a marked acute sympathetic response, and evidence exists for sympathetic participation in the development of cerebral vasospasm (VS). The purpose of this observational investigation...
8.
Moussouttas M, Bhatnager M, Huynh T, Lai E, Khoury J, Dombrowski K, et al.
Acta Neurochir (Wien)
. 2013 May;
155(8):1501-10.
PMID: 23636336
Introduction: Sympathetic activation promotes hemostasis, and subarachnoid hemorrhage (SAH) is associated with pronounced sympathetic activation. This investigation will assess whether catecholaminergic activity relates to venous thrombotic events in patients with...
9.
Kaludercic N, Carpi A, Nagayama T, Sivakumaran V, Zhu G, Lai E, et al.
Antioxid Redox Signal
. 2013 Apr;
20(2):267-80.
PMID: 23581564
Aims: Monoamine oxidases (MAOs) are mitochondrial flavoenzymes responsible for neurotransmitter and biogenic amines catabolism. MAO-A contributes to heart failure progression via enhanced norepinephrine catabolism and oxidative stress. The potential pathogenetic...
10.
Stauffer J, Orentas R, Lincoln E, Khan T, Salcedo R, Hixon J, et al.
Cancer Invest
. 2012 May;
30(5):343-63.
PMID: 22571338
Using two MYCN transgenic mouse strains, we established 10 transplantable neuroblastoma cell lines via serial orthotopic passage in the adrenal gland. Tissue arrays demonstrate that by histochemistry, vascularity, immunohistochemical staining...