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Edward S Schelegle

Explore the profile of Edward S Schelegle including associated specialties, affiliations and a list of published articles. Areas
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Articles 66
Citations 981
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Recent Articles
1.
Fothergill D, Borras E, McCartney M, Schelegle E, Davis C
J Breath Res . 2023 May; 17(3). PMID: 37207635
Prolonged exposure to hyperbaric hyperoxia can lead to pulmonary oxygen toxicity (POtox). POtox is a mission limiting factor for special operations forces divers using closed-circuit rebreathing apparatus and a potential...
2.
Borras E, Schrumpf L, Stephens N, Weimer B, Davis C, Schelegle E
J Chromatogr B Analyt Technol Biomed Life Sci . 2021 Mar; 1168:122588. PMID: 33690092
Ascorbic acid (AA) and uric acid (UA) are known as two of the major antioxidants in biological fluids. We report a novel liquid chromatography-mass spectrometry with time-of-flight (LC-MS-TOF) method for...
3.
Wong E, Tablin F, Schelegle E
PLoS One . 2020 Nov; 15(11):e0242147. PMID: 33166366
The aim of time-varying heart rate variability spectral analysis is to detect and quantify changes in the heart rate variability spectrum components during nonstationary events. Of the methods available, the...
4.
Shaffo F, Grodzki A, Schelegle E, Lein P
Toxicol Sci . 2018 Jun; 165(1):244-253. PMID: 29939342
Occupational and environmental exposures to organophosphorus pesticides (OPs) are associated with increased incidence of asthma and other pulmonary diseases. Although the canonical mechanism of OP neurotoxicity is inhibition of acetylcholinesterase...
5.
Wong E, Walby W, Wilson D, Tablin F, Schelegle E
Toxicol Sci . 2018 Feb; 163(1):140-151. PMID: 29394414
Particulate matter (PM) and ozone (O3) are dominant air pollutants that contribute to development and exacerbation of multiple cardiopulmonary diseases. Mature adults with cardiovascular disease (CVD) are particularly susceptible to...
6.
Miller L, Royer C, Pinkerton K, Schelegle E
ILAR J . 2017 Dec; 58(2):269-280. PMID: 29216343
The respiratory system consists of an integrated network of organs and structures that primarily function for gas exchange. In mammals, oxygen and carbon dioxide are transmitted through a complex respiratory...
7.
Crowley C, Fontaine J, Gerriets J, Schelegle E, Hyde D, Miller L
Toxicol Appl Pharmacol . 2017 May; 328:60-69. PMID: 28529118
Early life is a critical period for the progressive establishment of immunity in response to environmental stimuli; the impact of airborne challenges on this process is not well defined. In...
8.
Black C, Gerriets J, Fontaine J, Harper R, Kenyon N, Tablin F, et al.
Am J Respir Cell Mol Biol . 2017 Feb; 56(5):657-666. PMID: 28208028
The long-term health effects of wildfire smoke exposure in pediatric populations are not known. The objectives of this study were to determine if early life exposure to wildfire smoke can...
9.
Lynn T, Molloy E, Masterson J, Glynn S, Costello R, Avdalovic M, et al.
Am J Respir Cell Mol Biol . 2015 Sep; 54(4):562-73. PMID: 26414797
Bone morphogenetic protein (BMP) signaling is important for correct lung morphogenesis, and there is evidence of BMP signaling reactivation in lung diseases. However, little is known about BMP signaling patterns...
10.
Figueroa J, Mansoor J, Allen R, Davis C, Walby W, Aksenov A, et al.
J Breath Res . 2015 Apr; 9(2):026004. PMID: 25891856
With ascent to altitude, certain individuals are susceptible to high altitude pulmonary edema (HAPE), which in turn can cause disability and even death. The ability to identify individuals at risk...